ABIN965696

antibody from antibodies-online

Targeting: BRCA1 BRCC1, FANCS, PPP1R53, RNF53

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965696

Provider

antibodies-online

Product name

anti-Breast Cancer 1 (BRCA1) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human BRCA1 around the phosphorylation site of serine 1423 (H-G-SP-Q-P).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human

Host

Rabbit

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.

Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM
Genes & development 2006 Jan 1;20(1):34-46

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Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, Chung JH, Powell SN, Xia F
Molecular and cellular biology 2004 Jan;24(2):708-18

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BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function.

Arlt MF, Xu B, Durkin SG, Casper AM, Kastan MB, Glover TW
Molecular and cellular biology 2004 Aug;24(15):6701-9

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.

Kim ST, Xu B, Kastan MB
Genes & development 2002 Mar 1;16(5):560-70

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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.

Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT
Genes & development 2000 Dec 1;14(23):2989-3002