Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb66847 - Provider product page
- Provider
- Biorbyt
- Product name
- BMI1 antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal to BMI1.BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required tomaintain the transcriptionally repressive state of many genes, including Hox genes, throughoutdevelopment. PcG PRC1 complex acts via chromatin remodeling and modification of histones; itmediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in itsexpressibility. In the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligaseactivity of RNF2/RING2.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 100 ul
- Storage
- -20°C
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