Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN357748 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BMI1 Polycomb Ring Finger Oncogene (BMI1) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1.
The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.
HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.
Xia ZB, Anderson M, Diaz MO, Zeleznik-Le NJ
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 8;100(14):8342-7
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 8;100(14):8342-7
Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1.
Itahana K, Zou Y, Itahana Y, Martinez JL, Beausejour C, Jacobs JJ, Van Lohuizen M, Band V, Campisi J, Dimri GP
Molecular and cellular biology 2003 Jan;23(1):389-401
Molecular and cellular biology 2003 Jan;23(1):389-401
Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1.
Smith KS, Chanda SK, Lingbeek M, Ross DT, Botstein D, van Lohuizen M, Cleary ML
Molecular cell 2003 Aug;12(2):393-400
Molecular cell 2003 Aug;12(2):393-400
The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells.
Dimri GP, Martinez JL, Jacobs JJ, Keblusek P, Itahana K, Van Lohuizen M, Campisi J, Wazer DE, Band V
Cancer research 2002 Aug 15;62(16):4736-45
Cancer research 2002 Aug 15;62(16):4736-45
HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.
Bárdos JI, Saurin AJ, Tissot C, Duprez E, Freemont PS
The Journal of biological chemistry 2000 Sep 15;275(37):28785-92
The Journal of biological chemistry 2000 Sep 15;275(37):28785-92
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