Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN2839281 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-BMI (AA 257-286), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 257-286, C-Term
- Antibody clone number
- RB02926
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells.
Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.
Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis.
MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.
HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.
Wang X, Venugopal C, Manoranjan B, McFarlane N, O'Farrell E, Nolte S, Gunnarsson T, Hollenberg R, Kwiecien J, Northcott P, Taylor MD, Hawkins C, Singh SK
Oncogene 2012 Jan 12;31(2):187-99
Oncogene 2012 Jan 12;31(2):187-99
Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5.
Lewis A, Segditsas S, Deheragoda M, Pollard P, Jeffery R, Nye E, Lockstone H, Davis H, Clark S, Stamp G, Poulsom R, Wright N, Tomlinson I
Gut 2010 Dec;59(12):1680-6
Gut 2010 Dec;59(12):1680-6
Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis.
Sangiorgi E, Capecchi MR
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7101-6
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 28;106(17):7101-6
MLL repression domain interacts with histone deacetylases, the polycomb group proteins HPC2 and BMI-1, and the corepressor C-terminal-binding protein.
Xia ZB, Anderson M, Diaz MO, Zeleznik-Le NJ
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 8;100(14):8342-7
Proceedings of the National Academy of Sciences of the United States of America 2003 Jul 8;100(14):8342-7
HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.
Bárdos JI, Saurin AJ, Tissot C, Duprez E, Freemont PS
The Journal of biological chemistry 2000 Sep 15;275(37):28785-92
The Journal of biological chemistry 2000 Sep 15;275(37):28785-92
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC