Tissue expression
Cell line expression
Protein structure
TAPBP
TAP binding proteinTAPA
This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
|||||
LSBio | LS-C748410 | Polyclonal |
WB
ICC
IHC
|
||
antibodies-online | ABIN1875423 | Polyclonal |
WB
ICC
IHC
|
||
GeneTex | GTX16401 | Polyclonal |
WB
ICC
IHC
|
||
OriGene | TA332478 | Polyclonal |
WB
ICC
IHC
|
||
Novus Biologicals | NBP1-59071 | Polyclonal |
WB
ICC
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider