METAP2

gene product
MAP2, MNPEP, p67
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
249 antibodies from 28 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
OriGene
14 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
7 antibodies
Invitrogen Antibodies
4 antibodies
Abnova Corporation
5 antibodies
LifeSpan BioSciences, Inc.
55 antibodies
Novus Biologicals
1 antibody
Proteintech Group
1 antibody
R&D Systems
1 antibody
antibodies-online
89 antibodies
Biorbyt
15 antibodies
Aviva Systems Biology
4 antibodies
Acris Antibodies GmbH
4 antibodies
GeneTex
4 antibodies
RabMAbs
4 antibodies
Affinity Biosciences
1 antibody
Bethyl Laboratories
1 antibody
Boster Biological Technology
1 antibody
Sino Biological Inc.
1 antibody
Creative Biolabs
4 antibodies
ProSci
3 antibodies
Abgent
2 antibodies
Creative Diagnostics
4 antibodies
MyBioSource
3 antibodies
Cell Signaling Technology, Inc
1 antibody
St John's Laboratory
1 antibody
United States Biological
15 antibodies
Sigma-Aldrich
3 antibodies