Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 11264-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11264-1-AP, RRID:AB_10807096
- Product name
- ATG12 antibody
- Antibody type
- Polyclonal
- Description
- ATG12 antibody (Cat. #11264-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Licochalcone A promotes autophagy to ameliorate NAFLD by inhibiting the mTOR and regulating ULK1/Beclin1/VPS34 pathway.
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
Mechanisms of Intermittent Theta-Burst Stimulation Upregulates TFEB and Restores Autophagy to Play a Neuroprotective Role in the Acute Phase After Cerebral Ischemia Reperfusion.
Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy†.
ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Mitochondrial tRNA(Glu) 14693A > G Mutation, an "Enhancer" to the Phenotypic Expression of Leber's Hereditary Optic Neuropathy.
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer.
MiR-3653 blocks autophagy to inhibit epithelial-mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1.
TMEM175 downregulation participates in impairment of the autophagy related lysosomal dynamics following neonatal hypoxic-ischemic brain injury.
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Autophagy Alters Bladder Angiogenesis and Improves Bladder Hyperactivity in the Pathogenesis of Ketamine-Induced Cystitis in a Rat Model.
Sphingosine kinase 1 protects renal tubular epithelial cells from renal fibrosis via induction of autophagy.
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Li J, Zhang D, Liu P, Fang R, Li Y, Zhu Y, Dong M, Xie S, Liu Y, Wu J, Zhu G, Han J
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120333
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120333
Nitrate Promotes the Survival of Diabetic Skin Flaps by Enhancing Autophagy Through the AMPK Signaling Pathway.
Li M, Zhu L, Xu Y, Han Z
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132
The Journal of craniofacial surgery 2025 Sep 1;36(6):2127-2132
Mechanisms of Intermittent Theta-Burst Stimulation Upregulates TFEB and Restores Autophagy to Play a Neuroprotective Role in the Acute Phase After Cerebral Ischemia Reperfusion.
Zhang XY, Zhao YN, Gui LH, Han PP, Huang YY, Bi X
Neurochemical research 2025 Nov 27;51(1):4
Neurochemical research 2025 Nov 27;51(1):4
Multi-omics characterization of autophagy-related molecular features in intrahepatic cholestasis of pregnancy†.
Tang M, Luo M, Zhang L, Xiong L, Gong X, Zhou X, Yang J, Wang P, Zhao Z, Wu S, Xing S, Cai J, Yang X
Biology of reproduction 2025 Dec 16;113(6):1510-1522
Biology of reproduction 2025 Dec 16;113(6):1510-1522
ATRA-induced NEAT1 upregulation promotes autophagy during APL cell granulocytic differentiation.
Tang D, Wang H, Jiang Y, Chen M, Zhang G, Wu S, Wang Y
PloS one 2024;19(12):e0316109
PloS one 2024;19(12):e0316109
Hepatocyte-Specific HuR Protects Against Acetaminophen-Induced Liver Injury in Mice.
Lu L, Chen J, Jiang H, Li N, Li X, Liu Y, Zong C
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Journal of cellular and molecular medicine 2024 Nov;28(22):e70246
Mitochondrial tRNA(Glu) 14693A > G Mutation, an "Enhancer" to the Phenotypic Expression of Leber's Hereditary Optic Neuropathy.
Jin L, Gan D, He W, Wu N, Xiang S, Wei Y, Eriani G, Ji Y, Guan MX, Wang M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2401856
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2401856
LncRNA DDX11-AS1 Promotes Chemoresistance through LIN28A-Mediated ATG12 mRNA Stabilization in Breast Cancer.
Si X, Zhang G, Li M, Yao M, Shi X, Dong Z, Gao S
Pharmacology 2023;108(1):61-73
Pharmacology 2023;108(1):61-73
MiR-3653 blocks autophagy to inhibit epithelial-mesenchymal transition in breast cancer cells by targeting the autophagy-regulatory genes ATG12 and AMBRA1.
Song H, Zhao Z, Ma L, Zhang B, Song Y
Chinese medical journal 2023 Sep 5;136(17):2086-2100
Chinese medical journal 2023 Sep 5;136(17):2086-2100
TMEM175 downregulation participates in impairment of the autophagy related lysosomal dynamics following neonatal hypoxic-ischemic brain injury.
Zhang H, Tian Y, Yu W, Tong D, Ji Y, Qu X, Deng T, Li X, Xu Y
Journal of cellular physiology 2023 Oct;238(10):2512-2527
Journal of cellular physiology 2023 Oct;238(10):2512-2527
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Zhu H, Liu H, Chen X, Xu X, Zhang S, Xie D
Frontiers in cell and developmental biology 2022;10:971736
Frontiers in cell and developmental biology 2022;10:971736
Latcripin-7A from Lentinula edodes C(91-3) induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M
European journal of pharmacology 2021 Sep 15;907:174305
European journal of pharmacology 2021 Sep 15;907:174305
Autophagy Alters Bladder Angiogenesis and Improves Bladder Hyperactivity in the Pathogenesis of Ketamine-Induced Cystitis in a Rat Model.
Lu JH, Wu YH, Juan TJ, Lin HY, Lin RJ, Chueh KS, Lee YC, Chang CY, Juan YS
Biology 2021 May 30;10(6)
Biology 2021 May 30;10(6)
Sphingosine kinase 1 protects renal tubular epithelial cells from renal fibrosis via induction of autophagy.
Du C, Ren Y, Yao F, Duan J, Zhao H, Du Y, Xiao X, Duan H, Shi Y
The international journal of biochemistry & cell biology 2017 Sep;90:17-28
The international journal of biochemistry & cell biology 2017 Sep;90:17-28
Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway.
Du C, Zhang T, Xiao X, Shi Y, Duan H, Ren Y
The Biochemical journal 2017 Aug 2;474(16):2733-2747
The Biochemical journal 2017 Aug 2;474(16):2733-2747
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 11264-1-AP(ATG12 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The ATG12 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ATG12. This antibody recognizes human, mouse, rat antigen. The ATG12 antibody has been validated for the following applications: ELISA, WB, IHC analysis.