ATG12

Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]). [supplied by OMIM, Mar 2008]

Description

autophagy related 12

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

5:q22.3 (115828200 - 115841837)

Ensembl ID

ENSG00000145782  (ver. 99.38)

Orthologs

Mouse Atg12: ENSMUSG00000032905

UniProt

O94817

neXtProt

NX_O94817

Human splice variants
Mouse splice variants