PA1-21011
antibody from Invitrogen Antibodies
Targeting: DMD
BMD, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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Validation data
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- Product number
- PA1-21011 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-Dystrophin Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- PA1-21015 detects ERK1 in Human, Mouse and Rat samples. PA1-21015 has been successfully used in Immunohistochemistry (Paraffin) procedures. PA1-21015 immunogen corresponds to Synthetic peptide corresponding to the C-terminal region of the rat protein. .
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C, do not freeze
Submitted references The first exon duplication mouse model of Duchenne muscular dystrophy: A tool for therapeutic development.
Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.
Variable t-tubule organization and Ca2+ homeostasis across the atria.
Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle.
Vulin A, Wein N, Simmons TR, Rutherford AM, Findlay AR, Yurkoski JA, Kaminoh Y, Flanigan KM
Neuromuscular disorders : NMD 2015 Nov;25(11):827-34
Neuromuscular disorders : NMD 2015 Nov;25(11):827-34
Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice.
Wein N, Vulin A, Falzarano MS, Szigyarto CA, Maiti B, Findlay A, Heller KN, Uhlén M, Bakthavachalu B, Messina S, Vita G, Passarelli C, Brioschi S, Bovolenta M, Neri M, Gualandi F, Wilton SD, Rodino-Klapac LR, Yang L, Dunn DM, Schoenberg DR, Weiss RB, Howard MT, Ferlini A, Flanigan KM
Nature medicine 2014 Sep;20(9):992-1000
Nature medicine 2014 Sep;20(9):992-1000
Variable t-tubule organization and Ca2+ homeostasis across the atria.
Frisk M, Koivumäki JT, Norseng PA, Maleckar MM, Sejersted OM, Louch WE
American journal of physiology. Heart and circulatory physiology 2014 Aug 15;307(4):H609-20
American journal of physiology. Heart and circulatory physiology 2014 Aug 15;307(4):H609-20
Slowed relaxation and preserved maximal force in soleus muscles of mice with targeted disruption of the Serca2 gene in skeletal muscle.
Sjåland C, Lunde PK, Swift F, Munkvik M, Ericsson M, Lunde M, Boye S, Christensen G, Ellingsen Ø, Sejersted OM, Andersson KB
The Journal of physiology 2011 Dec 15;589(Pt 24):6139-55
The Journal of physiology 2011 Dec 15;589(Pt 24):6139-55
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Dystrophin in paraffin-embedded mouse heart tissue using a Dystrophin polyclonal antibody (Product # PA1-21011) at a dilution of 1:50.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Dystrophin in human skeletal muscle using a Dystrophin polyclonal antibody (Product # PA1-21011).