391404

antibody from BioLegend
Targeting: ACKR3 CMKOR1, CXCR7, GPR159, RDC1
Provider product page for 391404

Antibody data

Product number
391404 - Provider product page
Provider
BioLegend
Proper citation
BioLegend Cat#391404, RRID:AB_2565681
Product name
PE anti-human CXCR7
Antibody type
Monoclonal
Antigen
Other
Description
CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with a high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. The binding of a ligand to CXCR7 induces proliferation and migration of immature neurons, glia, and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells, and mature dendritic cells. Surface expression of CXCR7 has been also reported in tumor cells, activated endothelial cells, and fetal liver cells.
Reactivity
Human
Host
Mouse
Conjugate
Yellow dye
Antibody clone number
10D1-J16
Vial size
100 tests
Storage
2°C-8°C
Handling
Ambient RT
ACKR3 protein structure - 391404 shown in red.