ACKR3

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

Description

atypical chemokine receptor 3

Protein family

Cancer-related genes, G-protein coupled receptors, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas)

Chromosome

2:q37.3 (236567787 - 236582354)

Ensembl ID

ENSG00000144476  (ver. 99.38)

Orthologs

Mouse Ackr3: ENSMUSG00000044337

UniProt

P25106

neXtProt

NX_P25106

Human splice variants
Mouse splice variants