331111

antibody from BioLegend

Targeting: ACKR3 CMKOR1, CXCR7, GPR159, RDC1

Antibody data

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Validation data

Product number: 331111 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#331111, RRID:AB_1227618
Product name: Biotin anti-human/mouse CXCR7
Antibody type: Monoclonal
Antigen: Human CXCR7 transfectant
Description: CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and few other cell types.
Reactivity: Human, Mouse
Host: Mouse
Conjugate: Biotin
Isotype: IgG
Vial size: 25 µg
Concentration: 0.5 mg/ml
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

ACKR3 protein structure - 331111 shown in red.