Tissue expression
Cell line expression
Protein structure
AP5Z1
Adaptor related protein complex 5 subunit zeta 1KIAA0415, SPG48, zeta
This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011]
Top validated antibodies |
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Atlas Antibodies | ![]() |
8 references | Polyclonal |
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Novus Biologicals | ![]() |
1 references | Polyclonal |
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Proteintech Group | ![]() |
Monoclonal |
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Invitrogen Antibodies | ![]() |
Monoclonal |
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antibodies-online | ![]() |
Polyclonal |
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