SMC1A

gene product
DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
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960 antibodies from 41 providers.

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Novus Biologicals
34 antibodies
antibodies-online
320 antibodies
GeneTex
13 antibodies
OriGene
39 antibodies
Abnova Corporation
8 antibodies
Acris Antibodies GmbH
13 antibodies
Bethyl Laboratories
7 antibodies
Invitrogen Antibodies
21 antibodies
Signalway Antibody LLC
5 antibodies
LifeSpan BioSciences, Inc.
118 antibodies
St John's Laboratory
14 antibodies
Affinity Biosciences
4 antibodies
Boster Biological Technology
7 antibodies
Arigo
3 antibodies
Aviva Systems Biology
11 antibodies
Biorbyt
38 antibodies
Bioworld Technology, Inc
6 antibodies
Proteintech Group
2 antibodies
HUABIO Research
2 antibodies
Abgent
7 antibodies
Cell Signaling Technology, Inc
6 antibodies
ProSci
4 antibodies
Creative Biolabs
37 antibodies
NovoPro Bioscience Inc.
2 antibodies
RabMAbs
17 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
Abbexa
16 antibodies
MyBioSource
17 antibodies
R&D Systems
3 antibodies
Creative Diagnostics
6 antibodies
Leading Biology
5 antibodies
SignalChem
1 antibody
United States Biological
105 antibodies
Active Motif
2 antibodies
GenWay
7 antibodies
Abbiotec
1 antibody
RayBiotech, Inc.
1 antibody
Sigma-Aldrich
5 antibodies
EMD Millipore
4 antibodies
Exalpha Biologicals, Inc.
1 antibody