ABIN362223

antibody from antibodies-online

Targeting: SMC1A DXS423E, KIAA0178, SB1.8, SMC1L1, Smcb

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362223

Provider

antibodies-online

Product name

anti-Structural Maintenance of Chromosomes 1A (SMC1A) (pSer957) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer957 (G-S-S (p) -Q-G) derived from Human SMC1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pSer957

Isotype

IgG

Vial size

50 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation.

Yang XM, Mehta S, Uzri D, Jayaram M, Velmurugan S
Molecular and cellular biology 2004 Jun;24(12):5290-303

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage.

Kim ST, Xu B, Kastan MB
Genes & development 2002 Mar 1;16(5):560-70

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Novel meiosis-specific isoform of mammalian SMC1.

Revenkova E, Eijpe M, Heyting C, Gross B, Jessberger R
Molecular and cellular biology 2001 Oct;21(20):6984-98