Tissue expression
Cell line expression
Protein structure
GTF3A
General transcription factor IIIAAP2, TFIIIA
The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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LSBio | ![]() |
Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Affinity Biosciences | ![]() |
Polyclonal |
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Atlas Antibodies | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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