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- Western blot [1]
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- Product number
- HPA012495 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA012495, RRID:AB_1851804
- Product name
- Anti-OCRL
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human OCRL, Gene description: oculocerebrorenal syndrome of Lowe, Alternative Gene Names: OCRL1, Validated applications: IHC, WB, Uniprot ID: Q01968, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references A 3D Renal Proximal Tubule on Chip Model Phenocopies Lowe Syndrome and Dent II Disease Tubulopathy.
Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling.
Naik S, Wood AR, Ongenaert M, Saidiyan P, Elstak ED, Lanz HL, Stallen J, Janssen R, Smythe E, Erdmann KS
International journal of molecular sciences 2021 May 19;22(10)
International journal of molecular sciences 2021 May 19;22(10)
Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic
He K, Marsland III R, Upadhyayula S, Song E, Dang S, Capraro B, Wang W, Skillern W, Gaudin R, Ma M, Kirchhausen T
Nature 2017;552(7685):410-414
Nature 2017;552(7685):410-414
Recruitment of OCRL and Inpp5B to phagosomes by Rab5 and APPL1 depletes phosphoinositides and attenuates Akt signaling.
Bohdanowicz M, Balkin DM, De Camilli P, Grinstein S
Molecular biology of the cell 2012 Jan;23(1):176-87
Molecular biology of the cell 2012 Jan;23(1):176-87
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in EFO-21 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-OCRL antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
