Tissue expression
Cell line expression
Protein structure
OCRL
OCRL inositol polyphosphate-5-phosphataseDent-2, OCRL1
This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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Proteintech Group | ![]() |
5 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Atlas Antibodies | ![]() |
3 references | Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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