DPABH-18754

antibody from Creative Diagnostics
Targeting: ACTN1
Provider product page for DPABH-18754
Western blot
Immunohistochemistry

Antibody data

Product number
DPABH-18754 - Provider product page
Provider
Creative Diagnostics
Proper citation
Creative Diagnostics Cat#DPABH-18754, RRID:AB_2514837
Product name
Rabbit Anti-Human ACTN1 Polyclonal Antibody
Antibody type
Polyclonal
Description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 _L
Storage
Store at +4°C for short term storage. Long time storage is recommended at -20°C. Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
ACTN1 protein structure - DPABH-18754 shown in red.