Tissue expression
Cell line expression

ACTN1

gene product
 
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Antigen sequence

Conjugate

Epitope

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
494 antibodies from 38 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
2 antibodies
antibodies-online
122 antibodies
OriGene
12 antibodies
Novus Biologicals
32 antibodies
Invitrogen Antibodies
21 antibodies
LifeSpan BioSciences, Inc.
89 antibodies
GeneTex
6 antibodies
Aviva Systems Biology
4 antibodies
Santa Cruz Biotechnology
1 antibody
HUABIO Research
2 antibodies
Affinity Biosciences
4 antibodies
Atlas Antibodies
1 antibody
Biorbyt
38 antibodies
Cusabio Biotech Co., Ltd
12 antibodies
Abnova Corporation
5 antibodies
Cell Signaling Technology, Inc
4 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
R&D Systems
2 antibodies
Bioworld Technology, Inc
2 antibodies
Enzo Life Sciences
2 antibodies
Abbkine Scientific Co.Ltd.
5 antibodies
Acris Antibodies GmbH
6 antibodies
RabMAbs
5 antibodies
NovoPro Bioscience Inc.
4 antibodies
Antibodies.com
1 antibody
NSJ Bioreagents
1 antibody
Creative Biolabs
24 antibodies
MyBioSource
14 antibodies
Abgent
4 antibodies
ProSci
2 antibodies
Boster Biological Technology
1 antibody
United States Biological
39 antibodies
Abiocode, Inc.
3 antibodies
Creative Diagnostics
5 antibodies
Abbexa
8 antibodies
EMD Millipore
2 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
Leading Biology
3 antibodies