DUSP9

gene product
MKP-4, MKP4
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
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282 antibodies from 30 providers.

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Antibody
Proteintech Group
3 antibodies
OriGene
2 antibodies
antibodies-online
96 antibodies
Acris Antibodies GmbH
6 antibodies
Aviva Systems Biology
5 antibodies
LifeSpan BioSciences, Inc.
47 antibodies
NovoPro Bioscience Inc.
6 antibodies
Biorbyt
14 antibodies
GeneTex
2 antibodies
Affinity Biosciences
1 antibody
Invitrogen Antibodies
6 antibodies
Novus Biologicals
4 antibodies
Bioworld Technology, Inc
1 antibody
Abnova Corporation
6 antibodies
St John's Laboratory
2 antibodies
Atlas Antibodies
1 antibody
Abbkine Scientific Co.Ltd.
1 antibody
RabMAbs
1 antibody
MyBioSource
6 antibodies
Abbexa
10 antibodies
ProSci
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
39 antibodies
Creative Diagnostics
5 antibodies
Leading Biology
3 antibodies
Creative Biolabs
5 antibodies
Bioss
1 antibody
Boster Biological Technology
1 antibody
Sigma-Aldrich
3 antibodies
Abgent
2 antibodies