DPABH-25639

antibody from Creative Diagnostics

Targeting: HTR2C 5-HT2C, 5HTR2C, HTR1C

Western blot (Recommended by provider)

Antibody Data

Product number

DPABH-25639

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-25639, RRID:AB_2506504

Product name

Rabbit Anti-Human HTR2C Polyclonal Antibody

Antibody type

Polyclonal

Description

This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50ul, 100ul

Storage

Store at 4°C. Avoid freeze / thaw cycles.