HTR2C

gene product
5-HT2C, 5HTR2C, HTR1C
This gene encodes a seven-transmembrane G-protein-coupled receptor. The encoded protein responds to signaling through the neurotransmitter serotonin. The mRNA of this gene is subject to multiple RNA editing events, where adenosine residues encoded by the genome are converted to inosines. RNA editing is predicted to alter the structure of the second intracellular loop, thereby generating alternate protein forms with decreased ability to interact with G proteins. Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression. In addition, naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders. Alternative splicing results in multiple different transcript variants. [provided by RefSeq, Jan 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
470 antibodies from 32 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Biorbyt
25 antibodies
OriGene
12 antibodies
antibodies-online
157 antibodies
Affinity Biosciences
2 antibodies
Novus Biologicals
15 antibodies
LifeSpan BioSciences, Inc.
63 antibodies
Bioworld Technology, Inc
2 antibodies
NovoPro Bioscience Inc.
8 antibodies
Aviva Systems Biology
5 antibodies
Abnova Corporation
7 antibodies
Invitrogen Antibodies
9 antibodies
GeneTex
7 antibodies
R&D Systems
9 antibodies
Acris Antibodies GmbH
7 antibodies
Abgent
9 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
St John's Laboratory
4 antibodies
Arigo
1 antibody
United States Biological
59 antibodies
RabMAbs
5 antibodies
ProSci
4 antibodies
Creative Diagnostics
7 antibodies
Creative Biolabs
11 antibodies
MyBioSource
6 antibodies
RayBiotech, Inc.
6 antibodies
Sigma-Aldrich
4 antibodies
GenWay
4 antibodies
Abbexa
1 antibody