Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- PA5-27164 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- HTR2C Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- Recommended positive controls: IMR32, SK-N-AS, mouse placenta, rat brain. Predicted reactivity: Mouse (100%), Rat (100%), Dog (100%), Chimpanzee (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.68 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Effects of 5-Hydroxytryptamine Class 2 Receptor Antagonists on Bronchoconstriction and Pulmonary Remodeling Processes.
5-HT2B receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo.
Löfdahl A, Wenglén C, Rydell-Törmänen K, Westergren-Thorsson G, Larsson-Callerfelt AK
The American journal of pathology 2018 May;188(5):1113-1119
The American journal of pathology 2018 May;188(5):1113-1119
5-HT2B receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo.
Löfdahl A, Rydell-Törmänen K, Müller C, Martina Holst C, Thiman L, Ekström G, Wenglén C, Larsson-Callerfelt AK, Westergren-Thorsson G
Physiological reports 2016 Aug;4(15)
Physiological reports 2016 Aug;4(15)
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Figure 1 HFL -1 expression of 5- HT 2 receptors. Identification of 5- HT 2A (A), 5- HT 2B (B), and 5- HT 2C (C) receptors on cultured HFL -1 cells. Isotype-matched negative controls for 5- HT 2A (D), 5- HT 2B (E), and 5- HT 2C (F) receptor antibodies showed no positive receptor staining. Anti-5- HT 2 receptor antibodies (red), cell nuclear staining with DAPI (blue). Scale bars represent 40 mu m.