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- References [10]
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- Product number
- HPA020352 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA020352, RRID:AB_1853828
- Product name
- Anti-METTL16
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human METTL16, Gene description: methyltransferase like 16, Alternative Gene Names: METT10D, MGC3329, Validated applications: ICC, WB, Uniprot ID: Q86W50, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation
METTL16‐mediated N6‐methyladenosine modification of Soga1 enables proper chromosome segregation and chromosomal stability in colorectal cancer
METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
METTL16 promotes cell proliferation by up‐regulating cyclin D1 expression in gastric cancer
Localization of METTL16 at the Nuclear Periphery and the Nucleolus Is Cell Cycle-Specific and METTL16 Interacts with Several Nucleolar Proteins.
Characterization of METTL16 as a cytoplasmic RNA binding protein
N(6)-Adenosine Methylation in RNA and a Reduced m(3)G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions.
Methyltransferase-like protein 16 binds the 3′-terminal triple helix of MALAT1 long noncoding RNA
Xue M, Dong L, Zhang H, Li Y, Qiu K, Zhao Z, Gao M, Han L, Chan A, Li W, Leung K, Wang K, Pokharel S, Qing Y, Liu W, Wang X, Ren L, Bi H, Yang L, Shen C, Chen Z, Melstrom L, Li H, Timchenko N, Deng X, Huang W, Rosen S, Tian J, Xu L, Diao J, Chen C, Chen J, Shen B, Chen H, Su R
Journal of Hematology & Oncology 2024;17(1)
Journal of Hematology & Oncology 2024;17(1)
METTL16‐mediated N6‐methyladenosine modification of Soga1 enables proper chromosome segregation and chromosomal stability in colorectal cancer
Li J, Yang F, Wang Z, Zheng S, Zhang S, Wang C, He B, Wang J, Wang H
Cell Proliferation 2023;57(5)
Cell Proliferation 2023;57(5)
METTL3-Mediated m6A Modification Controls Splicing Factor Abundance and Contributes to Aggressive CLL
Wu Y, Jin M, Fernandez M, Hart K, Liao A, Ge X, Fernandes S, McDonald T, Chen Z, Röth D, Ghoda L, Marcucci G, Kalkum M, Pillai R, Danilov A, Li J, Chen J, Brown J, Rosen S, Siddiqi T, Wang L
Blood Cancer Discovery 2023;4(3):228-245
Blood Cancer Discovery 2023;4(3):228-245
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, Pokharel S, Gao M, Chen M, Shen C, Tan B, Small A, Wang K, Zhang Z, Qin X, Yang L, Wunderlich M, Zhang B, Mulloy J, Marcucci G, Chen C, Wei M, Su R, Chen J, Deng X
Cell Stem Cell 2023;30(1):52-68.e13
Cell Stem Cell 2023;30(1):52-68.e13
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis
Su R, Dong L, Li Y, Gao M, He P, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen C, Huang W, Horne D, Rosen S, He C, Chen J
Nature Cell Biology 2022;24(2):205-216
Nature Cell Biology 2022;24(2):205-216
METTL16 promotes cell proliferation by up‐regulating cyclin D1 expression in gastric cancer
Wang X, Zhang Y, Wang C, Li B, Zhang T, Zhou W, Cheng L, Huo M, Zhang C, He Y
Journal of Cellular and Molecular Medicine 2021;25(14):6602-6617
Journal of Cellular and Molecular Medicine 2021;25(14):6602-6617
Localization of METTL16 at the Nuclear Periphery and the Nucleolus Is Cell Cycle-Specific and METTL16 Interacts with Several Nucleolar Proteins.
Stixová L, Komůrková D, Svobodová Kovaříková A, Fagherazzi P, Bártová E
Life (Basel, Switzerland) 2021 Jul 8;11(7)
Life (Basel, Switzerland) 2021 Jul 8;11(7)
Characterization of METTL16 as a cytoplasmic RNA binding protein
Palazzo A, Nance D, Satterwhite E, Bhaskar B, Misra S, Carraway K, Mansfield K
PLOS ONE 2020;15(1):e0227647
PLOS ONE 2020;15(1):e0227647
N(6)-Adenosine Methylation in RNA and a Reduced m(3)G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions.
Svobodová Kovaříková A, Stixová L, Kovařík A, Komůrková D, Legartová S, Fagherazzi P, Bártová E
Cells 2020 Feb 4;9(2)
Cells 2020 Feb 4;9(2)
Methyltransferase-like protein 16 binds the 3′-terminal triple helix of MALAT1 long noncoding RNA
Brown J, Kinzig C, DeGregorio S, Steitz J
Proceedings of the National Academy of Sciences 2016;113(49):14013-14018
Proceedings of the National Academy of Sciences 2016;113(49):14013-14018
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-METTL16 antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
