NB100-1318
antibody from Novus Biologicals
		Targeting: ATP6AP2
		
		APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR	
	
	
	
	
Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
Reference
Comment
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- Product number
- NB100-1318 - Provider product page 
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1318, RRID:AB_2062207
- Product name
- Goat Polyclonal Renin R Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references		Colocalization of the (Pro)renin Receptor/Atp6ap2 with H+-ATPases in Mouse Kidney but Prorenin Does Not Acutely Regulate Intercalated Cell H+-ATPase Activity.
				
Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor.
				
(Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.
				
Regulation of the (pro)renin-renin receptor in cardiac remodelling.
				
Molecular evidence of a (pro)renin/ (pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2.
				
Location of prorenin receptors in primate substantia nigra: effects on dopaminergic cell death.
				
Characterization of a functional (pro)renin receptor in rat brain neurons.
				
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.
				
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.
				
		
	
			Daryadel A, Bourgeois S, Figueiredo MF, Gomes Moreira A, Kampik NB, Oberli L, Mohebbi N, Lu X, Meima ME, Danser AH, Wagner CA
PloS one 2016;11(1):e0147831
		PloS one 2016;11(1):e0147831
Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor.
			Mahmud H, Candido WM, van Genne L, Vreeswijk-Baudoin I, Yu H, van de Sluis B, van Deursen J, van Gilst WH, Silljé HH, de Boer RA
PloS one 2014;9(2):e89929
		PloS one 2014;9(2):e89929
(Pro)renin receptor triggers distinct angiotensin II-independent extracellular matrix remodeling and deterioration of cardiac function.
			Moilanen AM, Rysä J, Serpi R, Mustonen E, Szabò Z, Aro J, Näpänkangas J, Tenhunen O, Sutinen M, Salo T, Ruskoaho H
PloS one 2012;7(7):e41404
		PloS one 2012;7(7):e41404
Regulation of the (pro)renin-renin receptor in cardiac remodelling.
			Mahmud H, Silljé HH, Cannon MV, van Gilst WH, de Boer RA
Journal of cellular and molecular medicine 2012 Apr;16(4):722-9
		Journal of cellular and molecular medicine 2012 Apr;16(4):722-9
Molecular evidence of a (pro)renin/ (pro)renin receptor system in human intrauterine tissues in pregnancy and its association with PGHS-2.
			Pringle KG, Zakar T, Yates D, Mitchell CM, Hirst JJ, Lumbers ER
Journal of the renin-angiotensin-aldosterone system : JRAAS 2011 Sep;12(3):304-10
		Journal of the renin-angiotensin-aldosterone system : JRAAS 2011 Sep;12(3):304-10
Location of prorenin receptors in primate substantia nigra: effects on dopaminergic cell death.
			Valenzuela R, Barroso-Chinea P, Villar-Cheda B, Joglar B, Muñoz A, Lanciego JL, Labandeira-Garcia JL
Journal of neuropathology and experimental neurology 2010 Nov;69(11):1130-42
		Journal of neuropathology and experimental neurology 2010 Nov;69(11):1130-42
Characterization of a functional (pro)renin receptor in rat brain neurons.
			Shan Z, Cuadra AE, Sumners C, Raizada MK
Experimental physiology 2008 May;93(5):701-8
		Experimental physiology 2008 May;93(5):701-8
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.
			Ludwig J, Kerscher S, Brandt U, Pfeiffer K, Getlawi F, Apps DK, Schägger H
The Journal of biological chemistry 1998 May 1;273(18):10939-47
		The Journal of biological chemistry 1998 May 1;273(18):10939-47
Identification and characterization of a novel 9.2-kDa membrane sector-associated protein of vacuolar proton-ATPase from chromaffin granules.
			Ludwig J, Kerscher S, Brandt U, Pfeiffer K, Getlawi F, Apps DK, Schägger H
The Journal of biological chemistry 1998 May 1;273(18):10939-47
		The Journal of biological chemistry 1998 May 1;273(18):10939-47
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					Supportive validation
					
									
				
				- Submitted by
- Novus Biologicals (provider)
- Main image
 
- Experimental details
- Western Blot: Renin R Antibody [NB100-1318] - 2ug/ml of Mouse Kidney lysate (RIPA buffer, 35ug total protein per lane). Detected by chemiluminescence.
							
					Supportive validation
					
									
				
		- Submitted by
- Novus Biologicals (provider)
- Main image
 
- Experimental details
- Flow Cytometry: Renin R Antibody [NB100-1318] - analysis of paraformaldehyde fixed HeLa cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml followed by Alexa Fluor 488 secondary antibody (2ug/ml). IgG control: Unimmunized goat IgG (black line)