ATP6AP2

This gene encodes a protein that is associated with adenosine triphosphatases (ATPases). Proton-translocating ATPases have fundamental roles in energy conservation, secondary active transport, acidification of intracellular compartments, and cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and an extramembrane catalytic sector. The encoded protein has been found associated with the transmembrane sector of the V-type ATPases. [provided by RefSeq, Jul 2008]

Description

ATPase, H+ transporting, lysosomal accessory protein 2

Protein family

Disease related genes, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

X:p11.4 (40580908 - 40606637)

Ensembl ID

ENSG00000182220  (ver. 84.38)

Orthologs

Mouse Atp6ap2: ENSMUSG00000031007

UniProt

O75787

neXtProt

NX_O75787

Human splice variants
Mouse splice variants