MAGEE1

This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to cognitive disability. [provided by RefSeq, Mar 2010]

Description

MAGE family member E1

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

X:q13.3 (76427710 - 76431342)

Ensembl ID

ENSG00000198934  (ver. 99.38)

Orthologs

Mouse Magee1: ENSMUSG00000031227

UniProt

Q9HCI5

neXtProt

NX_Q9HCI5

Human splice variants
Mouse splice variants