Explore
Validate
LearnABIN250749
antibody from antibodies-online
Targeting: MED12
ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230
Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN250749 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Mediator Complex Subunit 12 (MED12) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 100 μL
- Storage
- Store at 4°C. Do not freeze.
- Handling
- Do not freeze.
Submitted references Immunohistochemical profiling of receptor tyrosine kinases, MED12, and TGF-βRII of surgically resected small cell lung cancer, and the potential of c-kit as a prognostic marker.
Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription.
Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.
Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines.
Control of ground-state pluripotency by allelic regulation of Nanog.
Core promoter recognition complex changes accompany liver development.
A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells.
Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis.
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling.
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.
Role for Med12 in regulation of Nanog and Nanog target genes.
Yokouchi H, Nishihara H, Harada T, Ishida T, Yamazaki S, Kikuchi H, Oizumi S, Uramoto H, Tanaka F, Harada M, Akie K, Sugaya F, Fujita Y, Takamura K, Kojima T, Higuchi M, Honjo O, Minami Y, Watanabe N, Goto A, Suzuki H, Dosaka-Akita H, Isobe H, Nishimura M, Munakata M
Oncotarget 2017 Jun 13;8(24):39711-39726
Oncotarget 2017 Jun 13;8(24):39711-39726
Temporal association of herpes simplex virus ICP4 with cellular complexes functioning at multiple steps in PolII transcription.
Wagner LM, DeLuca NA
PloS one 2013;8(10):e78242
PloS one 2013;8(10):e78242
Sox10 cooperates with the mediator subunit 12 during terminal differentiation of myelinating glia.
Vogl MR, Reiprich S, Küspert M, Kosian T, Schrewe H, Nave KA, Wegner M
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Apr 10;33(15):6679-90
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Apr 10;33(15):6679-90
Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines.
Valdez BC, Nieto Y, Murray D, Li Y, Wang G, Champlin RE, Andersson BS
Experimental hematology 2012 Oct;40(10):800-10
Experimental hematology 2012 Oct;40(10):800-10
Control of ground-state pluripotency by allelic regulation of Nanog.
Miyanari Y, Torres-Padilla ME
Nature 2012 Feb 12;483(7390):470-3
Nature 2012 Feb 12;483(7390):470-3
Core promoter recognition complex changes accompany liver development.
D'Alessio JA, Ng R, Willenbring H, Tjian R
Proceedings of the National Academy of Sciences of the United States of America 2011 Mar 8;108(10):3906-11
Proceedings of the National Academy of Sciences of the United States of America 2011 Mar 8;108(10):3906-11
A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells.
Langlais D, Couture C, Sylvain-Drolet G, Drouin J
Molecular endocrinology (Baltimore, Md.) 2011 Feb;25(2):348-59
Molecular endocrinology (Baltimore, Md.) 2011 Feb;25(2):348-59
Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida, and craniorachischisis.
Rocha PP, Bleiss W, Schrewe H
Birth defects research. Part A, Clinical and molecular teratology 2010 Aug;88(8):626-32
Birth defects research. Part A, Clinical and molecular teratology 2010 Aug;88(8):626-32
Med12 is essential for early mouse development and for canonical Wnt and Wnt/PCP signaling.
Rocha PP, Scholze M, Bleiss W, Schrewe H
Development (Cambridge, England) 2010 Aug;137(16):2723-31
Development (Cambridge, England) 2010 Aug;137(16):2723-31
MED19 and MED26 are synergistic functional targets of the RE1 silencing transcription factor in epigenetic silencing of neuronal gene expression.
Ding N, Tomomori-Sato C, Sato S, Conaway RC, Conaway JW, Boyer TG
The Journal of biological chemistry 2009 Jan 30;284(5):2648-56
The Journal of biological chemistry 2009 Jan 30;284(5):2648-56
Role for Med12 in regulation of Nanog and Nanog target genes.
Tutter AV, Kowalski MP, Baltus GA, Iourgenko V, Labow M, Li E, Kadam S
The Journal of biological chemistry 2009 Feb 6;284(6):3709-18
The Journal of biological chemistry 2009 Feb 6;284(6):3709-18
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ICC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
