Antibody data
- Antibody Data
- Antigen structure
- References [26]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13268-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13268-1-AP, RRID:AB_2123444
- Product name
- IDO1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IDO1 antibody (Cat. #13268-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Predicting Panel of Metabolism and Immune-Related Genes for the Prognosis of Human Ovarian Cancer.
Indoleamine-2,3-Dioxygenase 1 Deficiency Suppresses Seizures in Epilepsy.
Elevated mRNA Level of Y-Box Binding Protein 1 Indicates Unfavorable Prognosis Correlated with Macrophage Infiltration and T Cell Exhaustion in Luminal Breast Cancer.
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
IDO1 as a new immune biomarker for diabetic nephropathy and its correlation with immune cell infiltration.
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Tryptophan potentiates CD8+ T cells against cancer cells by TRIP12 tryptophanylation and surface PD-1 downregulation.
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer.
Mifepristone regulates Tregs function mediated by dendritic cells through suppressing the expression of TGF-β.
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Combined Metabolomic Analysis of Plasma and Tissue Reveals a Prognostic Risk Score System and Metabolic Dysregulation in Esophageal Squamous Cell Carcinoma.
IDO1 Expression Increased After Neoadjuvant Therapy Predicts Poor Pathologic Response and Prognosis in Esophageal Squamous Cell Carcinoma.
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Nrf2 modulates immunosuppressive ability and cellular senescence of human umbilical cord mesenchymal stem cells.
Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion.
1,25(OH)2D3 mitigate cancer-related fatigue in tumor-bearing mice: Integrating network pharmacological analysis.
Enhanced cancer therapy through synergetic photodynamic/immune checkpoint blockade mediated by a liposomal conjugate comprised of porphyrin and IDO inhibitor.
Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons.
Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress.
Multiple myeloma cell-derived IL-32γ increases the immunosuppressive function of macrophages by promoting indoleamine 2,3-dioxygenase (IDO) expression.
Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells.
Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response.
Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide.
Ammonium salt modified mesoporous silica nanoparticles for dual intracellular-responsive gene delivery.
Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B.
Interferon-γ regulates the function of mesenchymal stem cells from oral lichen planus via indoleamine 2,3-dioxygenase activity.
Zhang L, Sun W, Ren W, Zhang J, Xu G
Frontiers in cell and developmental biology 2021;9:690542
Frontiers in cell and developmental biology 2021;9:690542
Indoleamine-2,3-Dioxygenase 1 Deficiency Suppresses Seizures in Epilepsy.
Deng N, Hu J, Hong Y, Ding Y, Xiong Y, Wu Z, Xie W
Frontiers in cellular neuroscience 2021;15:638854
Frontiers in cellular neuroscience 2021;15:638854
Elevated mRNA Level of Y-Box Binding Protein 1 Indicates Unfavorable Prognosis Correlated with Macrophage Infiltration and T Cell Exhaustion in Luminal Breast Cancer.
Lv Z, Xue C, Zhang L, Sun J, Bo C
Cancer management and research 2021;13:6411-6428
Cancer management and research 2021;13:6411-6428
Novel roles of VAT1 expression in the immunosuppressive action of diffuse gliomas.
Yang P, Wang K, Zhang C, Wang Z, Liu Q, Wang J, Jiang T, Shan X
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2589-2600
Cancer immunology, immunotherapy : CII 2021 Sep;70(9):2589-2600
IDO1 as a new immune biomarker for diabetic nephropathy and its correlation with immune cell infiltration.
Yu K, Li D, Xu F, Guo H, Feng F, Ding Y, Wan X, Sun N, Zhang Y, Fan J, Liu L, Yang H, Yang X
International immunopharmacology 2021 May;94:107446
International immunopharmacology 2021 May;94:107446
Total glycosides from stems of Cistanche tubulosa alleviate depression-like behaviors: bidirectional interaction of the phytochemicals and gut microbiota.
Fan L, Peng Y, Wang J, Ma P, Zhao L, Li X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Mar;83:153471
Tryptophan potentiates CD8+ T cells against cancer cells by TRIP12 tryptophanylation and surface PD-1 downregulation.
Qin R, Zhao C, Wang CJ, Xu W, Zhao JY, Lin Y, Yuan YY, Lin PC, Li Y, Zhao S, Huang Y
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
GCH1 induces immunosuppression through metabolic reprogramming and IDO1 upregulation in triple-negative breast cancer.
Wei JL, Wu SY, Yang YS, Xiao Y, Jin X, Xu XE, Hu X, Li DQ, Jiang YZ, Shao ZM
Journal for immunotherapy of cancer 2021 Jul;9(7)
Journal for immunotherapy of cancer 2021 Jul;9(7)
Mifepristone regulates Tregs function mediated by dendritic cells through suppressing the expression of TGF-β.
Li Y, Cao L, Qian Z, Guo Q, Niu X, Huang L
Immunopharmacology and immunotoxicology 2021 Feb;43(1):85-93
Immunopharmacology and immunotoxicology 2021 Feb;43(1):85-93
Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells.
Chen C, Chencheng Z, Cuiying L, Xiaokun G
Frontiers in cellular neuroscience 2020;14:8
Frontiers in cellular neuroscience 2020;14:8
Combined Metabolomic Analysis of Plasma and Tissue Reveals a Prognostic Risk Score System and Metabolic Dysregulation in Esophageal Squamous Cell Carcinoma.
Chen Z, Dai Y, Huang X, Chen K, Gao Y, Li N, Wang D, Chen A, Yang Q, Hong Y, Zeng S, Mao W
Frontiers in oncology 2020;10:1545
Frontiers in oncology 2020;10:1545
IDO1 Expression Increased After Neoadjuvant Therapy Predicts Poor Pathologic Response and Prognosis in Esophageal Squamous Cell Carcinoma.
Jiao R, Zheng X, Sun Y, Feng Z, Song S, Ge H
Frontiers in oncology 2020;10:1099
Frontiers in oncology 2020;10:1099
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Ebokaiwe AP, Njoya EM, Sheng Y, Zhang Z, Li S, Zhou Z, Qiang Z, Peng T, Hussein AA, Zhang G, Lu X, Li L, Wang F
Toxicology and applied pharmacology 2020 Oct 1;404:115203
Toxicology and applied pharmacology 2020 Oct 1;404:115203
Nrf2 modulates immunosuppressive ability and cellular senescence of human umbilical cord mesenchymal stem cells.
Jie Z, Huan Y, Mengyun W, Yasha L, Huafeng P, Ke Y
Biochemical and biophysical research communications 2020 Jun 11;526(4):1021-1027
Biochemical and biophysical research communications 2020 Jun 11;526(4):1021-1027
Prunella vulgaris L. attenuates experimental autoimmune thyroiditis by inducing indoleamine 2,3-dioxygenase 1 expression and regulatory T cell expansion.
Qiu H, Zhang J, Guo Q, Zhang Y, Zhong X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110288
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110288
1,25(OH)2D3 mitigate cancer-related fatigue in tumor-bearing mice: Integrating network pharmacological analysis.
Zhou YT, Li SS, Ai M, Chen H, Liu YX, Li BY, Zhao Y, Cai WW, Hou B, Ni LL, Xu F, Qiu LY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110256
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110256
Enhanced cancer therapy through synergetic photodynamic/immune checkpoint blockade mediated by a liposomal conjugate comprised of porphyrin and IDO inhibitor.
Huang Z, Wei G, Zeng Z, Huang Y, Huang L, Shen Y, Sun X, Xu C, Zhao C
Theranostics 2019;9(19):5542-5557
Theranostics 2019;9(19):5542-5557
Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons.
Bando H, Lee Y, Sakaguchi N, Pradipta A, Sakamoto R, Tanaka S, Ma JS, Sasai M, Yamamoto M
Frontiers in cellular and infection microbiology 2019;9:140
Frontiers in cellular and infection microbiology 2019;9:140
Curcumin relieves depressive-like behaviors via inhibition of the NLRP3 inflammasome and kynurenine pathway in rats suffering from chronic unpredictable mild stress.
Zhang WY, Guo YJ, Han WX, Yang MQ, Wen LP, Wang KY, Jiang P
International immunopharmacology 2019 Feb;67:138-144
International immunopharmacology 2019 Feb;67:138-144
Multiple myeloma cell-derived IL-32γ increases the immunosuppressive function of macrophages by promoting indoleamine 2,3-dioxygenase (IDO) expression.
Yan H, Dong M, Liu X, Shen Q, He D, Huang X, Zhang E, Lin X, Chen Q, Guo X, Chen J, Zheng G, Wang G, He J, Yi Q, Cai Z
Cancer letters 2019 Apr 1;446:38-48
Cancer letters 2019 Apr 1;446:38-48
Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells.
Bando H, Sakaguchi N, Lee Y, Pradipta A, Ma JS, Tanaka S, Lai DH, Liu J, Lun ZR, Nishikawa Y, Sasai M, Yamamoto M
Frontiers in immunology 2018;9:2073
Frontiers in immunology 2018;9:2073
Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response.
Bando H, Lee Y, Sakaguchi N, Pradipta A, Ma JS, Tanaka S, Cai Y, Liu J, Shen J, Nishikawa Y, Sasai M, Yamamoto M
mBio 2018 Oct 9;9(5)
mBio 2018 Oct 9;9(5)
Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide.
Dang R, Zhou X, Tang M, Xu P, Gong X, Liu Y, Jiao H, Jiang P
European journal of nutrition 2018 Apr;57(3):893-906
European journal of nutrition 2018 Apr;57(3):893-906
Ammonium salt modified mesoporous silica nanoparticles for dual intracellular-responsive gene delivery.
Li Y, Hei M, Xu Y, Qian X, Zhu W
International journal of pharmaceutics 2016 Sep 25;511(2):689-702
International journal of pharmaceutics 2016 Sep 25;511(2):689-702
Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B.
Yoshio S, Sugiyama M, Shoji H, Mano Y, Mita E, Okamoto T, Matsuura Y, Okuno A, Takikawa O, Mizokami M, Kanto T
Hepatology (Baltimore, Md.) 2016 Jan;63(1):83-94
Hepatology (Baltimore, Md.) 2016 Jan;63(1):83-94
Interferon-γ regulates the function of mesenchymal stem cells from oral lichen planus via indoleamine 2,3-dioxygenase activity.
Zhang Z, Han Y, Song J, Luo R, Jin X, Mu D, Su S, Ji X, Ren YF, Liu H
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015 Jan;44(1):15-27
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2015 Jan;44(1):15-27
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IDO1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IDO1. This antibody recognizes human antigen. The IDO1 antibody has been validated for the following applications: ELISA, WB analysis.