FRMPD3

This gene encodes a protein that contains a PDZ (post synaptic density protein (PSD95), Drosophila disc large tumor suppressor (Dlg1), and zonula occludens-1 protein (zo-1) domain at the N-terminus followed by a FERM domain. The encoded protein is involved in signal transduction. The PDZ domain is thought to function in protein-protein interactions, mainly by binding to specific C-terminal peptides of other proteins. The FERM domain is found in proteins that are localized to the plasma membrane and are associated with the cytoskeleton. [provided by RefSeq, May 2017]

Description

FERM and PDZ domain containing 3

Tissue specificity

Tissue enhanced (brain, ovary, thyroid gland)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

X:q22.3 (107522450 - 107605251)

Ensembl ID

ENSG00000147234  (ver. 103.38)

Orthologs

Mouse Frmpd3: ENSMUSG00000042425

UniProt

Q5JV73

neXtProt

NX_Q5JV73

Human splice variants
Mouse splice variants