Tissue expression
Cell line expression
GMPR2
gene productThis gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of guanosine monophosphate (GMP) to inosine monophosphate (IMP). The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]
- Description
- Guanosine monophosphate reductase 2
- Tissue specificity
- Low tissue specificity
- Subcell location
- Nucleoplasm, Nucleoli
- Predicted location
- Intracellular
- Protein family
- Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
- Chromosome
- 14:q12 (24232422 - 24239242)
- Ensembl ID
- ENSG00000100938 (ver. 103.38)
- Orthologs
- Mouse Gmpr2: ENSMUSG00000002326
- UniProt
- Q9P2T1
- neXtProt
- NX_Q9P2T1
Human splice variants
Mouse splice variants
Ensembl | UniProt | RefSeq | Entrez |
---|---|---|---|
ENSMUST00000002397 ENSMUSP00000002397 |
Q99L27.139 Q99L27 | NP_818773.1 NP_818773 | Gmpr2 105446 |
ENSMUST00000227178 ENSMUSP00000154721 |
Gmpr2 105446 | ||
ENSMUST00000227914 ENSMUSP00000154349 |
Gmpr2 105446 |
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.