FNab05234

antibody from FineTest Biotech

Targeting: MMP12 HME

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Immunocytochemistry

Immunohistochemistry

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Validation data

Product number: FNab05234 - Provider product page
Provider: FineTest Biotech
Product name: MMP12 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: MMP12(Matrix metalloproteinase-12) is a 54 kDa proenzyme that is processed into a 45 kDa and then a 22 kDa active form(15723202). MMP9 and MMP12 promote intimal thickening by independent cleavage of N-cadherin, which elevates vascular smooth muscle cell proliferation via beta-catenin signalling. Its overexpression in myeloid lineage cells plays a key role in modulating myelopoiesis, immune suppression, and lung tumorigenesis(PMID: 21378275).
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: matrix metallopeptidase 12(macropha ge elastase)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

MMP12 protein structure - FNab05234 shown in red.