MMP12

gene product
HME
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
591 antibodies from 37 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
14 antibodies
Abgent
5 antibodies
R&D Systems
3 antibodies
antibodies-online
200 antibodies
Boster Biological Technology
3 antibodies
Abnova Corporation
10 antibodies
Biorbyt
30 antibodies
OriGene
18 antibodies
GeneTex
7 antibodies
NovoPro Bioscience Inc.
3 antibodies
St John's Laboratory
6 antibodies
Aviva Systems Biology
3 antibodies
Invitrogen Antibodies
5 antibodies
LifeSpan BioSciences, Inc.
118 antibodies
Proteintech Group
1 antibody
Acris Antibodies GmbH
8 antibodies
Santa Cruz Biotechnology
1 antibody
RabMAbs
4 antibodies
Abbkine Scientific Co.Ltd.
3 antibodies
ProSci
4 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Bioworld Technology, Inc
1 antibody
NSJ Bioreagents
3 antibodies
Creative Biolabs
32 antibodies
Enzo Life Sciences
2 antibodies
MyBioSource
14 antibodies
United States Biological
55 antibodies
EMD Millipore
3 antibodies
Arigo
1 antibody
Creative Diagnostics
6 antibodies
Sigma-Aldrich
4 antibodies
Abbexa
3 antibodies
RayBiotech, Inc.
3 antibodies
Everest Biotech
1 antibody
GenWay
2 antibodies