ABIN358027

antibody from antibodies-online

Targeting: APEX1 APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

ABIN358027

Provider

antibodies-online

Product name

anti-APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1) (AA 40-70), (N-Term) antibody

Antibody type

Polyclonal

Description

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reactivity

Human

Host

Rabbit

Epitope

N-Term, AA 40-70

Vial size

0.4 mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Association between genetic polymorphisms of DNA base excision repair genes and evolution of precancerous gastric lesions in a Chinese population.

Li WQ, Zhang L, Ma JL, Zhang Y, Li JY, Pan KF, You WC
Carcinogenesis 2009 Mar;30(3):500-5

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A polymorphism in the APE1 gene promoter is associated with lung cancer risk.

Lo YL, Jou YS, Hsiao CF, Chang GC, Tsai YH, Su WC, Chen KY, Chen YM, Huang MS, Hu CY, Chen CJ, Hsiung CA
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009 Jan;18(1):223-9

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APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

Vascotto C, Fantini D, Romanello M, Cesaratto L, Deganuto M, Leonardi A, Radicella JP, Kelley MR, D'Ambrosio C, Scaloni A, Quadrifoglio F, Tell G
Molecular and cellular biology 2009 Apr;29(7):1834-54

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Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene.

Bhakat KK, Izumi T, Yang SH, Hazra TK, Mitra S
The EMBO journal 2003 Dec 1;22(23):6299-309