Tissue expression
Cell line expression
Protein structure

APEX1

Apurinic/apyrimidinic endodeoxyribonuclease 1
APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1 
The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases. [provided by RefSeq, Dec 2019]
More gene data

All Antibodies

 

Filters

Application

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antigen sequence

Epitope

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
1065 antibodies from 47 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
55 antibodies
Invitrogen Antibodies
41 antibodies
Proteintech Group
3 antibodies
GeneTex
11 antibodies
NSJ Bioreagents
7 antibodies
antibodies-online
275 antibodies
OriGene
60 antibodies
Atlas Antibodies
2 antibodies
Biorbyt
149 antibodies
NovoPro Bioscience Inc.
2 antibodies
St John's Laboratory
8 antibodies
Enzo Life Sciences
2 antibodies
Santa Cruz Biotechnology
1 antibody
Boster Biological Technology
5 antibodies
Abnova Corporation
14 antibodies
HUABIO Research
4 antibodies
FineTest Biotech
2 antibodies
Cusabio Biotech Co., Ltd
12 antibodies
Affinity Biosciences
2 antibodies
Aviva Systems Biology
10 antibodies
Everest Biotech
1 antibody
Bioworld Technology, Inc
2 antibodies
Acris Antibodies GmbH
15 antibodies
Arigo
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
Aladdin Scientific Corporation
1 antibody
Antibodies.com
1 antibody
R&D Systems
2 antibodies
Abgent
10 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Signalway Antibody LLC
1 antibody
ProSci
9 antibodies
Creative Diagnostics
7 antibodies
MyBioSource
19 antibodies
RabMAbs
6 antibodies
United States Biological
74 antibodies
Creative Biolabs
28 antibodies
Abbexa
15 antibodies
Leading Biology
11 antibodies
RayBiotech, Inc.
5 antibodies
GenWay
5 antibodies
MilliporeSigma / Merck KGaA
5 antibodies
Abbiotec
1 antibody
Active Motif
1 antibody
CPTAC
1 antibody