APEX1

gene product
APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
856 antibodies from 41 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
55 antibodies
GeneTex
11 antibodies
NSJ Bioreagents
5 antibodies
antibodies-online
275 antibodies
Invitrogen Antibodies
8 antibodies
OriGene
56 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
137 antibodies
NovoPro Bioscience Inc.
2 antibodies
Proteintech Group
2 antibodies
Enzo Life Sciences
2 antibodies
Santa Cruz Biotechnology
1 antibody
Boster Biological Technology
6 antibodies
Abnova Corporation
14 antibodies
Biorbyt
37 antibodies
Affinity Biosciences
2 antibodies
Aviva Systems Biology
10 antibodies
Bioworld Technology, Inc
2 antibodies
Acris Antibodies GmbH
15 antibodies
St John's Laboratory
8 antibodies
Arigo
2 antibodies
Cell Signaling Technology, Inc
2 antibodies
Antibodies.com
1 antibody
Everest Biotech
1 antibody
R&D Systems
2 antibodies
Abgent
10 antibodies
Abbkine Scientific Co.Ltd.
4 antibodies
Signalway Antibody LLC
1 antibody
ProSci
9 antibodies
Creative Diagnostics
7 antibodies
MyBioSource
19 antibodies
Creative Biolabs
24 antibodies
RabMAbs
6 antibodies
United States Biological
74 antibodies
RayBiotech, Inc.
5 antibodies
GenWay
5 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
5 antibodies
Abbiotec
1 antibody
Active Motif
1 antibody