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Targeting: APEX1
APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1
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- Antibody Data
- Antigen structure
- References [4]
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- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN257862 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-APEX Nuclease (Multifunctional DNA Repair Enzyme) 1 (APEX1) (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human
- Host
- Goat
- Epitope
- N-Term
- Vial size
- 0.1 mg
- Storage
- Store at -20°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references Monoclonal antibodies against pools of mono- and polyacetylated peptides selectively recognize acetylated lysines within the context of the original antigen.
Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.
Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice.
Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.
Sandomenico A, Focà A, Sanguigno L, Caporale A, Focà G, Pignalosa A, Corvino G, Caragnano A, Beltrami AP, Antoniali G, Tell G, Leonardi A, Ruvo M
mAbs 2016 Nov Dec;8(8):1575-1589
mAbs 2016 Nov Dec;8(8):1575-1589
Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.
Bhakat KK, Sengupta S, Adeniyi VF, Roychoudhury S, Nath S, Bellot LJ, Feng D, Mantha AK, Sinha M, Qiu S, Luxon BA
Oncotarget 2016 Apr 19;7(16):22590-604
Oncotarget 2016 Apr 19;7(16):22590-604
Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice.
Allen D, Herbert DC, McMahan CA, Rotrekl V, Sobol RW, Wilson SH, Walter CA
Biology of reproduction 2008 Nov;79(5):824-31
Biology of reproduction 2008 Nov;79(5):824-31
Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes.
Demple B, Herman T, Chen DS
Proceedings of the National Academy of Sciences of the United States of America 1991 Dec 15;88(24):11450-4
Proceedings of the National Academy of Sciences of the United States of America 1991 Dec 15;88(24):11450-4
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
