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antibody from Novus Biologicals
Targeting: NLRP3
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NBP1-97601 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-97601, RRID:AB_11189153
- Product name
- Mouse Monoclonal NLRP3/NALP3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. Recognizes human NLRP3/NALP3.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.05 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Purple sweet potato color attenuated NLRP3 inflammasome by inducing autophagy to delay endothelial senescence.
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response.
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Sun C, Diao Q, Lu J, Zhang Z, Wu D, Wang X, Xie J, Zheng G, Shan Q, Fan S, Hu B, Zheng Y
Journal of cellular physiology 2019 May;234(5):5926-5939
Journal of cellular physiology 2019 May;234(5):5926-5939
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M
PLoS pathogens 2009 Aug;5(8):e1000559
PLoS pathogens 2009 Aug;5(8):e1000559
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response.
Kummer JA, Broekhuizen R, Everett H, Agostini L, Kuijk L, Martinon F, van Bruggen R, Tschopp J
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007 May;55(5):443-52
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007 May;55(5):443-52
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J
Immunity 2004 Mar;20(3):319-25
Immunity 2004 Mar;20(3):319-25
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J
Immunity 2004 Mar;20(3):319-25
Immunity 2004 Mar;20(3):319-25
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Frozen: NLRP3/NALP3 Antibody (Nalpy3-b) [NBP1-97601] - Staining of endogenous NLRP3/NALP3 in epithelial layer of human tonsil (frozen section) using NLRP3/NALP3 (human), mAb (Nalpy3-b). Method: 5uM frozen section of tissue are dried and fixed with aceton. Tissue is washed with PBS and incubated with NLRP3/NALP3 (human), mAb (Nalpy3-b).
