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LearnNBP2-03947
antibody from Novus Biologicals
Targeting: NLRP3
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- NBP2-03947 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal NLRP3/NALP3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration.
Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms.
Kosmidou C, Efstathiou NE, Hoang MV, Notomi S, Konstantinou EK, Hirano M, Takahashi K, Maidana DE, Tsoka P, Young L, Gragoudas ES, Olsen TW, Morizane Y, Miller JW, Vavvas DG
Scientific reports 2018 Jan 11;8(1):461
Scientific reports 2018 Jan 11;8(1):461
Inhibition of NLRP3 Inflammasome Prevents LPS-Induced Inflammatory Hyperalgesia in Mice: Contribution of NF-κB, Caspase-1/11, ASC, NOX, and NOS Isoforms.
Dolunay A, Senol SP, Temiz-Resitoglu M, Guden DS, Sari AN, Sahan-Firat S, Tunctan B
Inflammation 2017 Apr;40(2):366-386
Inflammation 2017 Apr;40(2):366-386
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: NLRP3/NALP3 Antibody (8N8E9) [NBP2-03947] - Analysis using NALP3 monoclonal antibody. (A), (B) and the recombinant human NALP3 Pyrin doman protein immunogen (C) probed with 5 ug/ml (tranfected) or 0.5 ug/ml (recombinant) of NALP3 antibody. HRP secondary antibody and ECL substrate solution were used for this test.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: NLRP3/NALP3 Antibody (8N8E9) [NBP2-03947] - Analysis of extracts from mouse spleen and Jurkat cells using NALP3 antibody (NBP2-03947) at 1:100.
