NB100-41104
antibody from Novus Biologicals
Targeting: NLRP3
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, DFNA34, FCAS, FCU, MWS, NALP3, PYPAF1
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB100-41104 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-41104, RRID:AB_789305
- Product name
- Goat Polyclonal NLRP3/NALP3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This antibody is expected to recognise all five reported isoforms (NP_004886.3
- Reactivity
- Human
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references IL-1 beta but not the NALP3 inflammasome is an important determinant of endothelial cell responses to necrotic/dangerous trophoblastic debris.
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
Wei J, Chen Q, James JL, Stone PR, Chamley LW
Placenta 2015 Dec;36(12):1385-92
Placenta 2015 Dec;36(12):1385-92
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3.
Kanneganti TD, Ozören N, Body-Malapel M, Amer A, Park JH, Franchi L, Whitfield J, Barchet W, Colonna M, Vandenabeele P, Bertin J, Coyle A, Grant EP, Akira S, Núñez G
Nature 2006 Mar 9;440(7081):233-6
Nature 2006 Mar 9;440(7081):233-6
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: NLRP3/NALP3 Antibody [NB100-41104] - Human Tonsil shows focal and interstitial staining of the inflammatory elements close to the epithelia of the tonsil crypts.