12335-1-AP
antibody from Proteintech Group
Targeting: CXCL1
FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
Antibody data
- Antibody Data
- Antigen structure
- References [102]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
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- Product number
- 12335-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12335-1-AP, RRID:AB_2087568
- Product name
- CXCL1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CXCL1 antibody (Cat. #12335-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multi-omics reveals that 4'-O-β-D-glucosyl-5-O-methylvisamminol ameliorates acute liver injury by modulating the miR-30e-3p/Tfrc axis and a multi-dimensional network of ferroptosis, inflammation, metabolism, and gut microbiota.
Kojic acid inhibits melanoma progression by targeting the MYC-CCNA2/KPNA2 axis.
SB225002 enhances radiosensitivity in cervical cancer via direct neutrophil inhibition and tumor cell suppression.
Single-cell RNA sequencing analysis identified GARP-expressing myeloid cells that deteriorate postinfarct myocardial remodeling.
Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models.
Histone lactylation increases CXCL1 expression for neutrophil infiltration and immune escape in pancreatic cancer.
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Thlaspi arvense attenuates colitis-associated colorectal tumorigenesis through suppression of neutrophil recruitment via the NOD/NF-κB pathway.
Chronic Psychological Stress Activates TRP/TAM/CXCL1 Signaling to Promote Breast Cancer Adipocyte Lipolysis via KEAP1 m(6)A Demethylation.
Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis.
IL-17A drives a fibroblast-neutrophil-NET axis to exacerbate immunopathology in the lung with diffuse alveolar damage.
Kisspeptin Suppresses the Growth of Primary Pterygial Cells via Inhibiting Chemokine (C-X-C Motif) Ligands in Microenvironment.
USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice.
Lysosome stress response and mitochondria injury are the earliest detectable alteration in FSGS.
Long noncoding RNA NONRATT007487.2 drives cancer-induced bone pain progression through direct interaction with CXCL1.
NSUN2 enhances the stability of PTPRD mRNA via m(5)C methylation to aggravate astrocyte activation.
The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.
Transition of pseudorabies virus from latency to reactivation state selectively triggered by pathogenic bacteria.
A Non-Invasive Approach to Intracellular Measurement in Solar Lentigo: Investigating Mitochondrial Dysfunction and Senescence Mechanisms Associated with Excessive Melanin Deposition.
Caspase-6/Gasdermin C-Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2-Dependent Recruitment of Myeloid-Derived Suppressor Cells.
Immunodynamic axis of fibroblast-driven neutrophil infiltration in acute pancreatitis: NF-κB-HIF-1α-CXCL1.
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Dictamnus dasycarpus turcz. Attenuates collagen-induced rheumatoid arthritis in DBA/1J mice through inhibiting IL-17 signaling pathway.
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
Deficiency of inducible nitric oxide synthase (iNOS) enhances MC903-induced atopic dermatitis-like inflammation in mice.
Aberrant Notch-signaling promotes tumor angiogenesis in esophageal squamous-cell carcinoma.
NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression.
Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis.
Unraveling the Role of METTL3 in Helicobacter pylori-induced gastritis via m6A-CXCL1/NF-κB modulation.
Inflammation-triggered Gli1(+) stem cells engage with extracellular vesicles to prime aberrant neutrophils to exacerbate periodontal immunopathology.
Langhans giant cells regulate cutaneous immune responses during mycobacterial infection through CXCL1/CXCL2 secretion.
A spatially resolved transcriptome landscape during thyroid cancer progression.
Targeting Reprogrammed Cancer-Associated Fibroblasts with Engineered Mesenchymal Stem Cell Extracellular Vesicles for Pancreatic Cancer Treatment.
SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.
Identification of potential biomarkers of gout through weighted gene correlation network analysis.
The Zeb1-Cxcl1 axis impairs the antitumor immune response by inducing M2 macrophage polarization in breast cancer.
Identification of immune-associated genes for the diagnosis of ulcerative colitis-associated carcinogenesis via integrated bioinformatics analysis.
Identifying key inflammatory genes in psoriasis via weighted gene co-expression network analysis: Potential targets for therapy.
Bioinformatics Identification and Validation of Angiogenesis-Related Genes in Myocardial Ischemic Reperfusion Injury.
ACSL6-activated IL-18R1-NF-κB promotes IL-18-mediated tumor immune evasion and tumor progression.
Quercetin alleviates liver fibrosis via regulating glycolysis of liver sinusoidal endothelial cells and neutrophil infiltration.
Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.
Mesenchymal stromal cells alleviate APAP-induced liver injury via extracellular vesicle-mediated regulation of the miR-186-5p/CXCL1 axis.
Integrative metabolomics and proteomics reveal the effect and mechanism of Zi Qi decoction on alleviating liver fibrosis.
APEX1 in intestinal epithelium triggers neutrophil infiltration and intestinal barrier damage in ulcerative colitis.
CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs.
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Enhancing precision medicine: a nomogram for predicting platinum resistance in epithelial ovarian cancer.
TRPV3 promotes sebocyte inflammation via transcriptional modulating TLR2 in acne.
Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.
TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils.
Aging aggravates aortic aneurysm and dissection via miR-1204-MYLK signaling axis in mice.
Integrin β1-rich extracellular vesicles of kidney recruit Fn1+ macrophages to aggravate ischemia-reperfusion-induced inflammation.
Mefunidone Inhibits Inflammation, Oxidative Stress, and Epithelial-Mesenchymal Transition in Lens Epithelial Cells.
Single-cell transcriptome profiles the heterogeneity of tumor cells and microenvironments for different pathological endometrial cancer and identifies specific sensitive drugs.
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy.
Electroacupuncture alleviates ulcerative colitis by targeting CXCL1: evidence from the transcriptome and validation.
Single-cell transcriptomes reveal a molecular link between diabetic kidney and retinal lesions.
Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer.
Single-cell analysis reveals immune cellular components in odontogenic keratocysts.
Chronic psychological stress promotes breast cancer pre-metastatic niche formation by mobilizing splenic MDSCs via TAM/CXCL1 signaling.
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Microglial IL-1RA ameliorates brain injury after ischemic stroke by inhibiting astrocytic CXCL1-mediated neutrophil recruitment and microvessel occlusion.
IL4I1-catalyzed tryptophan metabolites mediate the anti-inflammatory function of cytokine-primed human muscle stem cells.
Construction and evaluation of a novel prognostic risk model of aging-related genes in bladder cancer.
PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation.
ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells.
Regorafenib prevents the development of emphysema in a murine elastase model.
Ryanodine receptor 2 promotes colorectal cancer metastasis by the ROS/BACH1 axis.
CXCR2 signaling might have a tumor-suppressive role in patients with cholangiocarcinoma.
The Infiltration of Neutrophil Granulocytes Due to Loss of PTEN Was Associated with Poor Response to Immunotherapy in Renal Cell Carcinoma.
Ethanol promoting the upregulation of C-X-C Motif Chemokine Ligand 1(CXCL1) and C-X-C Motif Chemokine Ligand 6(CXCL6) in models of early alcoholic liver disease.
PAD4 controls chemoattractant production and neutrophil trafficking in malaria.
Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3-Lgr4 axis.
Discovery of Orally Available Retinoic Acid Receptor-Related Orphan Receptor γ-t/Dihydroorotate Dehydrogenase Dual Inhibitors for the Treatment of Refractory Inflammatory Bowel Disease.
Emerging Role of Dermal White Adipose Tissue in Modulating Hair Follicle Development During Aging.
The CXCL1-CXCR2 Axis Mediates Tubular Injury in Diabetic Nephropathy Through the Regulation of the Inflammatory Response.
Aiduqing formula suppresses breast cancer metastasis via inhibiting CXCL1-mediated autophagy.
Conjugation with nanodiamonds via hydrazone bond fundamentally alters intracellular distribution and activity of doxorubicin.
Oral microbiota affects the efficacy and prognosis of radiotherapy for colorectal cancer in mouse models.
Treatment of severe pneumonia by hinokitiol in a murine antimicrobial-resistant pneumococcal pneumonia model.
Low-Dose Radiation Promotes Invasion and Migration of A549 Cells by Activating the CXCL1/NF-κB Signaling Pathway.
The P72R Polymorphism in R248Q/W p53 Mutants Modifies the Mutant Effect on Epithelial to Mesenchymal Transition Phenotype and Cell Invasion via CXCL1 Expression.
CXCL1 as an Unfavorable Prognosis Factor Negatively Regulated by DACH1 in Non-small Cell Lung Cancer.
Aryl hydrocarbon receptor modulates stroke-induced astrogliosis and neurogenesis in the adult mouse brain.
Unsaturated Aldehyde Acrolein Promotes Retinal Glial Cell Migration.
Nur77 limits endothelial barrier disruption to LPS in the mouse lung.
Cancer-associated fibroblasts enhance tumor-associated macrophages enrichment and suppress NK cells function in colorectal cancer.
The antagonist of CXCR1 and CXCR2 protects db/db mice from metabolic diseases through modulating inflammation.
Maresin1 regulates neutrophil recruitment and IL-10 expression in Aspergillus fumigatus keratitis.
Metformin blocks myeloid-derived suppressor cell accumulation through AMPK-DACH1-CXCL1 axis.
Protective function of interleukin 27 in colitis-associated cancer via suppression of inflammatory cytokines in intestinal epithelial cells.
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.
SLC39A4 expression is associated with enhanced cell migration, cisplatin resistance, and poor survival in non-small cell lung cancer.
Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis.
Overexpression of Chemokine (C-X-C) ligand 1 (CXCL1) associated with tumor progression and poor prognosis in hepatocellular carcinoma.
Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo.
IL-1 alpha regulates CXCL1, CXCL10 and ICAM1 in network form in oral keratinocytes.
Induction of bone loss by pathobiont-mediated Nod1 signaling in the oral cavity.
Cancer associated fibroblasts express pro-inflammatory factors in human breast and ovarian tumors.
CXCR1 as a novel target for directing reactive T cells toward melanoma: implications for adoptive cell transfer immunotherapy.
Transduction of tumor-specific T cells with CXCR2 chemokine receptor improves migration to tumor and antitumor immune responses.
Zhang T, Zou R, Chen Z, Li Y, Sun X, Sun X
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158022
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158022
Kojic acid inhibits melanoma progression by targeting the MYC-CCNA2/KPNA2 axis.
Chen Y, Wang Q, Shi Y, Chen J, Liu J
Gene 2026 May 5;989:150047
Gene 2026 May 5;989:150047
SB225002 enhances radiosensitivity in cervical cancer via direct neutrophil inhibition and tumor cell suppression.
Ni Y, Zhou X, Tang Y, Ren W, Liang X, Lin Y, Shi H, Qing F, Alu A, Pi R, Liu J, Zhao X, Luo M, Wei X
Cancer letters 2026 Jan 28;638:218153
Cancer letters 2026 Jan 28;638:218153
Single-cell RNA sequencing analysis identified GARP-expressing myeloid cells that deteriorate postinfarct myocardial remodeling.
Tomimatsu M, Obana M, Tanaka S, Kajiura R, Nagano R, Matsumoto K, Yokota K, Kominami S, Ito T, Suzuki S, Motooka D, Liu YC, Seno S, Okuzaki D, Nagatomo I, Maeda M, Fukada SI, Okada Y, Fujio Y
American journal of physiology. Heart and circulatory physiology 2026 Jan 1;330(1):H12-H30
American journal of physiology. Heart and circulatory physiology 2026 Jan 1;330(1):H12-H30
Characterizing Chemokine Signaling Pathways and Hub Genes in Calcium Oxalate-Induced Kidney Stone Formation: Insights from Rodent Models.
Wang B, Tan Z, She W, Wang X, Guan X, Tao Z, Guo F, Xu H, Deng Y
Biochemical genetics 2026 Feb;64(1):430-445
Biochemical genetics 2026 Feb;64(1):430-445
Histone lactylation increases CXCL1 expression for neutrophil infiltration and immune escape in pancreatic cancer.
Zhang P, Ma J, Wan Y, Li C, Liu L, He M, Zhang N, Ma Y, Hu J, Zhao L, Zhong Z, Lei X, Gong J, Zeng T, Ma J, Da Y, Zhou Z, Yang J, Wang X, Gong T, Zhang C
Nature communications 2026 Feb 9;17(1)
Nature communications 2026 Feb 9;17(1)
Tumor-Associated Macrophage-Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF-κB Pathway.
Xia R, Qi D, Ji B, Dai Y, Kong X
Cancer science 2026 Apr;117(4):1026-1042
Cancer science 2026 Apr;117(4):1026-1042
Thlaspi arvense attenuates colitis-associated colorectal tumorigenesis through suppression of neutrophil recruitment via the NOD/NF-κB pathway.
Wang Z, Wang W, Wang C, Dong B, Sun Y, He X, Bi L, Wang Y
Chinese medicine 2026 Apr 17;21(1)
Chinese medicine 2026 Apr 17;21(1)
Chronic Psychological Stress Activates TRP/TAM/CXCL1 Signaling to Promote Breast Cancer Adipocyte Lipolysis via KEAP1 m(6)A Demethylation.
Zhan D, She Y, Zhang X, Zhang J, Wang S, Hong S, Zheng Y, Wang N, Wang Z
Research (Washington, D.C.) 2025;8:0980
Research (Washington, D.C.) 2025;8:0980
Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis.
Guo L, Ge J, Cheng L, Zhang X, Wu Z, Liu M, Jiang H, Gong W, Liu Y
PloS one 2025;20(12):e0338880
PloS one 2025;20(12):e0338880
IL-17A drives a fibroblast-neutrophil-NET axis to exacerbate immunopathology in the lung with diffuse alveolar damage.
Su D, Li L, Xie H, Ai L, Wang Y, Yang B, Zhou D, Hu L, Yang H
Frontiers in immunology 2025;16:1574246
Frontiers in immunology 2025;16:1574246
Kisspeptin Suppresses the Growth of Primary Pterygial Cells via Inhibiting Chemokine (C-X-C Motif) Ligands in Microenvironment.
Wu P, Liu S, Xu T, Zhao G
Current eye research 2025 Sep;50(9):894-902
Current eye research 2025 Sep;50(9):894-902
USP48 protects against myocardial ischemia-reperfusion injury by stabilizing and upregulating CNN1 in type 1 diabetes mice.
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Metabolism: clinical and experimental 2025 Sep;170:156326
Metabolism: clinical and experimental 2025 Sep;170:156326
Lysosome stress response and mitochondria injury are the earliest detectable alteration in FSGS.
Dahlke E, Promnitz J, Miranda MT, Saudenova M, Mollet G, Theilig F
Scientific reports 2025 Oct 13;15(1):35570
Scientific reports 2025 Oct 13;15(1):35570
Long noncoding RNA NONRATT007487.2 drives cancer-induced bone pain progression through direct interaction with CXCL1.
Jiang H, Wang L, Xu Y, Dai Z, Chen J, Zheng D, Zheng H
The Korean journal of pain 2025 Oct 1;38(4):378-390
The Korean journal of pain 2025 Oct 1;38(4):378-390
NSUN2 enhances the stability of PTPRD mRNA via m(5)C methylation to aggravate astrocyte activation.
Wang J, Zhang X, Zhang T, Yang Q, Liu J
Brain research 2025 Oct 1;1864:149799
Brain research 2025 Oct 1;1864:149799
The chemosensitizing activity of betulinic acid in suppressing macrophage polarization through GSK-3β/β-catenin/CXCL1 signaling in breast cancer.
Xu Z, Si J, Liang A, Zhang Y, Gong J, Li G, Zhong Y, Yu M, Feng R, Li X, Chang J, Wang N
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov 25;148:157304
Transition of pseudorabies virus from latency to reactivation state selectively triggered by pathogenic bacteria.
Yang D, Yang M, Guo S, Guo H, Li Y, Kuang Y, Li H, Zhang Y, Zhang S, Liu Q, Chen H, Wang X
Science advances 2025 Nov 21;11(47):eadw4206
Science advances 2025 Nov 21;11(47):eadw4206
A Non-Invasive Approach to Intracellular Measurement in Solar Lentigo: Investigating Mitochondrial Dysfunction and Senescence Mechanisms Associated with Excessive Melanin Deposition.
Nurani AM, Shibata T, Inoue D
International journal of molecular sciences 2025 Nov 11;26(22)
International journal of molecular sciences 2025 Nov 11;26(22)
Caspase-6/Gasdermin C-Mediated Tumor Cell Pyroptosis Promotes Colorectal Cancer Progression Through CXCL2-Dependent Recruitment of Myeloid-Derived Suppressor Cells.
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2411375
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 May;12(20):e2411375
Immunodynamic axis of fibroblast-driven neutrophil infiltration in acute pancreatitis: NF-κB-HIF-1α-CXCL1.
Wang Q, Zhang X, Han C, Lv Z, Zheng Y, Liu X, Du Z, Liu T, Xue D, Li T, Wang L
Cellular & molecular biology letters 2025 May 7;30(1):57
Cellular & molecular biology letters 2025 May 7;30(1):57
Tumor-derived exosomal CCT6A serves as a matchmaker introducing chemokines to tumor-associated macrophages in pancreatic ductal adenocarcinoma.
Ma T, Guo WW, Zhang M, He W, Dongzhi C, Gongye X, Xia P, Chai Y, Chen Z, Zhu Y, Qu C, Liu J, Yang Z, Ma W, Tian M, Yuan Y
Cell death & disease 2025 May 15;16(1):382
Cell death & disease 2025 May 15;16(1):382
Dictamnus dasycarpus turcz. Attenuates collagen-induced rheumatoid arthritis in DBA/1J mice through inhibiting IL-17 signaling pathway.
Liu Y, Li L, Sun Y, Wang S, Jiang P, Chen Q, Zhang L, Hao Z, Yang X, Yan J, Pan J, Guan W, Xu Z, Zhou Y, Lv S, Kuang H, Yang B
Journal of ethnopharmacology 2025 Mar 13;343:119458
Journal of ethnopharmacology 2025 Mar 13;343:119458
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
Chang J, Lu J, Liu Q, Xiang T, Zhang S, Yi Y, Li D, Liu T, Liu Z, Chen X, Dong Z, Li C, Yi H, Yu S, Huang L, Qu F, Wang M, Wang D, Dong H, Cheng G, Zhu L, Li J, Li C, Wu P, Xie X, Teschendorff AE, Lin D, Wang X, Wu C
Cancer cell 2025 Mar 10;43(3):380-397.e7
Cancer cell 2025 Mar 10;43(3):380-397.e7
Deficiency of inducible nitric oxide synthase (iNOS) enhances MC903-induced atopic dermatitis-like inflammation in mice.
Luo J, Li C, Zhu Y, Guo R, Huang J, Yu H, Sun M, Zhu Q, Guo Q, Li Y, Guo P, Su L, Hu L
Biochemical and biophysical research communications 2025 Jul 22;771:152028
Biochemical and biophysical research communications 2025 Jul 22;771:152028
Aberrant Notch-signaling promotes tumor angiogenesis in esophageal squamous-cell carcinoma.
Li C, Wu P, Xie X, Chen X, Chen L, Zhu L, Xuan Z, Liu T, Tan W, Zhang S, Lin D, Wu C
Signal transduction and targeted therapy 2025 Jul 22;10(1):233
Signal transduction and targeted therapy 2025 Jul 22;10(1):233
NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression.
Xu W, Liu J, Liu Q, Xu J, Zhou L, Liang Z, Huang H, Huang B, Xiao GG, Guo J
Cell reports 2025 Feb 25;44(2):115226
Cell reports 2025 Feb 25;44(2):115226
Equol promotes osteogenic differentiation of hPDLSCs by inhibiting oxidative stress via IL1B/NF-κB/CXCL1 signaling axis.
Jiang X, Chen X, He L, Qin D, Nie M, Li C, Liu X
Chemico-biological interactions 2025 Feb 1;407:111367
Chemico-biological interactions 2025 Feb 1;407:111367
Unraveling the Role of METTL3 in Helicobacter pylori-induced gastritis via m6A-CXCL1/NF-κB modulation.
Lu Q, Wang Z, Cao S, Wang H, Li N, Hu Y, Ding W, Zuo W, Hong J
Cell death & disease 2025 Aug 18;16(1):625
Cell death & disease 2025 Aug 18;16(1):625
Inflammation-triggered Gli1(+) stem cells engage with extracellular vesicles to prime aberrant neutrophils to exacerbate periodontal immunopathology.
Cai XY, Zheng CX, Guo H, Fan SY, Huang XY, Chen J, Liu JX, Gao YR, Liu AQ, Liu JN, Zhang XH, Ma C, Wang H, Fu F, Peng P, Xu HK, Sui BD, Xuan K, Jin Y
Cellular & molecular immunology 2025 Apr;22(4):371-389
Cellular & molecular immunology 2025 Apr;22(4):371-389
Langhans giant cells regulate cutaneous immune responses during mycobacterial infection through CXCL1/CXCL2 secretion.
Jiang Y, Jiang H, Zou Y, Wang Z, Gan T, Zeng R, Shi Y, Zhang W, Wang H
International immunopharmacology 2025 Apr 16;152:114447
International immunopharmacology 2025 Apr 16;152:114447
A spatially resolved transcriptome landscape during thyroid cancer progression.
Liao T, Zeng Y, Xu W, Shi X, Shen C, Du Y, Zhang M, Zhang Y, Li L, Ding P, Hu W, Huang Z, Fung MHM, Ji Q, Wang Y, Li S, Wei W
Cell reports. Medicine 2025 Apr 15;6(4):102043
Cell reports. Medicine 2025 Apr 15;6(4):102043
Targeting Reprogrammed Cancer-Associated Fibroblasts with Engineered Mesenchymal Stem Cell Extracellular Vesicles for Pancreatic Cancer Treatment.
Zhou P, Ding X, Du X, Wang L, Zhang Y
Biomaterials research 2024;28:0050
Biomaterials research 2024;28:0050
SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.
Pan J, Liang H, Zhou L, Lu W, Huo B, Liu R, Huang P
Frontiers in immunology 2024;15:1512981
Frontiers in immunology 2024;15:1512981
Identification of potential biomarkers of gout through weighted gene correlation network analysis.
Wang X, Yang B, Xiong T, Qiu Y, Qin Y, Liang X, Lu D, Yang X
Frontiers in immunology 2024;15:1367019
Frontiers in immunology 2024;15:1367019
The Zeb1-Cxcl1 axis impairs the antitumor immune response by inducing M2 macrophage polarization in breast cancer.
Ou Y, Jiang HM, Wang YJ, Shuai QY, Cao LX, Guo M, Qi CC, Li ZX, Shi J, Hu HY, Liu YX, Zuo SY, Chen X, Feng MD, Shi Y, Sun PQ, Wang H, Yang S
American journal of cancer research 2024;14(9):4378-4397
American journal of cancer research 2024;14(9):4378-4397
Identification of immune-associated genes for the diagnosis of ulcerative colitis-associated carcinogenesis via integrated bioinformatics analysis.
Cang X, Li N, Qi J, Chen H, Xing H, Qiu J, Tian Y, Huang S, Deng P, Gao F, Chaulagain RP, Ullah U, Wang C, Liu L, Jin S
Frontiers in oncology 2024;14:1475189
Frontiers in oncology 2024;14:1475189
Identifying key inflammatory genes in psoriasis via weighted gene co-expression network analysis: Potential targets for therapy.
Li H, Wang X, Zhu J, Yang B, Lou J
Biomolecules & biomedicine 2024 Sep 6;24(5):1133-1149
Biomolecules & biomedicine 2024 Sep 6;24(5):1133-1149
Bioinformatics Identification and Validation of Angiogenesis-Related Genes in Myocardial Ischemic Reperfusion Injury.
Wu L, Zhou Z, Zeng Y, Yang S, Zhang Q
Frontiers in bioscience (Landmark edition) 2024 Sep 29;29(10):347
Frontiers in bioscience (Landmark edition) 2024 Sep 29;29(10):347
ACSL6-activated IL-18R1-NF-κB promotes IL-18-mediated tumor immune evasion and tumor progression.
Di Y, Wang Z, Xiao J, Zhang X, Ye L, Wen X, Qin J, Lu L, Wang X, He W
Science advances 2024 Sep 20;10(38):eadp0719
Science advances 2024 Sep 20;10(38):eadp0719
Quercetin alleviates liver fibrosis via regulating glycolysis of liver sinusoidal endothelial cells and neutrophil infiltration.
Chen X, Wang Y, Wan J, Dou X, Zhang C, Sun M, Ye F
Biomolecules & biomedicine 2024 Oct 17;24(6):1806-1815
Biomolecules & biomedicine 2024 Oct 17;24(6):1806-1815
Cancer-Associated Endocrine Cells Participate in Pancreatic Carcinogenesis.
Chen Y, Yin X, Xu R, Ruze R, Song J, Yin C, Hu C, Wang C, Xu Q, Zhao Y
Gastroenterology 2024 Nov;167(6):1167-1182.e23
Gastroenterology 2024 Nov;167(6):1167-1182.e23
Mesenchymal stromal cells alleviate APAP-induced liver injury via extracellular vesicle-mediated regulation of the miR-186-5p/CXCL1 axis.
Zhao E, Liang R, Li P, Lu D, Chen S, Tan W, Qin Y, Zhang Y, Zhang Y, Zhang Q, Liu Q
Stem cell research & therapy 2024 Nov 3;15(1):392
Stem cell research & therapy 2024 Nov 3;15(1):392
Integrative metabolomics and proteomics reveal the effect and mechanism of Zi Qi decoction on alleviating liver fibrosis.
Chen X, Wang Y, Dou X, Wan J, Zhou J, Li T, Yu J, Ye F
Scientific reports 2024 Nov 22;14(1):28943
Scientific reports 2024 Nov 22;14(1):28943
APEX1 in intestinal epithelium triggers neutrophil infiltration and intestinal barrier damage in ulcerative colitis.
Chen Q, Chen T, Xiao H, Wang F, Li C, Hu N, Bao L, Tong X, Feng Y, Xu Y, Li C, Zhu JW, Wang D, Li MX
Free radical biology & medicine 2024 Nov 20;225:359-373
Free radical biology & medicine 2024 Nov 20;225:359-373
CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1-CXCR2 induced NETs.
Xiong G, Chen Z, Liu Q, Peng F, Zhang C, Cheng M, Ling R, Chen S, Liang Y, Chen D, Zhou Q
Journal for immunotherapy of cancer 2024 May 9;12(5)
Journal for immunotherapy of cancer 2024 May 9;12(5)
Macrophage SHP2 Deficiency Alleviates Diabetic Nephropathy via Suppression of MAPK/NF-κB- Dependent Inflammation.
Han X, Wei J, Zheng R, Tu Y, Wang M, Chen L, Xu Z, Zheng L, Zheng C, Shi Q, Ying H, Liang G
Diabetes 2024 May 1;73(5):780-796
Diabetes 2024 May 1;73(5):780-796
Enhancing precision medicine: a nomogram for predicting platinum resistance in epithelial ovarian cancer.
Li R, Xiong Z, Ma Y, Li Y, Yang Y, Ma S, Ha C
World journal of surgical oncology 2024 Mar 21;22(1):81
World journal of surgical oncology 2024 Mar 21;22(1):81
TRPV3 promotes sebocyte inflammation via transcriptional modulating TLR2 in acne.
Wei Z, Gao M, Liu Y, Zeng R, Liu J, Sun S, Li S, Hu L, Xiang R, Mo R, Song Z, Chen Z, Bao D, Hua D, Zouboulis CC, Feng Y, Li J, Yang Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167195
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167195
Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts.
Chen X, Cheng G, Zhu L, Liu T, Yang X, Liu R, Ou Z, Zhang S, Tan W, Lin D, Wu C
Cell reports. Medicine 2024 Jun 18;5(6):101576
Cell reports. Medicine 2024 Jun 18;5(6):101576
TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils.
Shen T, Cui G, Chen H, Huang L, Song W, Zu J, Zhang W, Xu C, Dong L, Zhang Y
Neural regeneration research 2024 Jun 1;19(6):1375-1384
Neural regeneration research 2024 Jun 1;19(6):1375-1384
Aging aggravates aortic aneurysm and dissection via miR-1204-MYLK signaling axis in mice.
Liu ZL, Li Y, Lin YJ, Shi MM, Fu MX, Li ZQ, Ning DS, Zeng XM, Liu X, Cui QH, Peng YM, Zhou XM, Hu YR, Liu JS, Liu YJ, Wang M, Zhang CX, Kong W, Ou ZJ, Ou JS
Nature communications 2024 Jul 16;15(1):5985
Nature communications 2024 Jul 16;15(1):5985
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Investigative ophthalmology & visual science 2024 Dec 2;65(14):17
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Frontiers in immunology 2023;14:1187574
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Communications biology 2023 Sep 5;6(1):912
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Frontiers in physiology 2021;12:782677
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- COLO 320 cells were subjected to SDS PAGE followed by western blot with 12335-1-AP(CXCL1 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The CXCL1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CXCL1. This antibody recognizes human, mouse antigen. The CXCL1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.