Tissue expression
Cell line expression
Protein structure
CXCL1
C-X-C motif chemokine ligand 1FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Monoclonal |
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R&D Systems | ![]() |
11 references | Monoclonal |
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Proteintech Group | ![]() |
51 references | Polyclonal |
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Novus Biologicals | ![]() |
2 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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