AMM03439G

antibody from Leading Biology

Targeting: CXCL1 FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03439G

Provider

Leading Biology

Product name

CXCL1 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

7A11

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.