RA0489

antibody from Oursmab

Targeting: TTR CTS, CTS1, HsT2651, PALB

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0489

Provider

Oursmab

Product name

Coramitug (Biosimilar Reference Antibody) (Misfolded TTR)

Antibody type

Monoclonal

Description

Coramitug (formerly PRX004) is an investigational humanized monoclonal antibody developed by Novo Nordisk (from Prothena) for treating Transthyretin Amyloidosis with Cardiomyopathy (ATTR-CM), a heart condition where misfolded TTR protein builds up as amyloid. It works by clearing these harmful TTR amyloid deposits, showing promise in reducing disease markers like NT-proBNP in Phase 2 trials and advancing to Phase 3 (CLEOPATTRA study) to assess its impact on heart failure.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.