Tissue expression
Cell line expression
Protein structure
MFGE8
Milk fat globule EGF and factor V/VIII domain containingBA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
2 references | Monoclonal |
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NSJ Bioreagents | ![]() |
3 references | Monoclonal |
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Boster Biological Technology | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Monoclonal |
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OriGene | ![]() |
1 references | Monoclonal |
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