Tissue expression
Cell line expression

DEPDC5

gene product
DEP.5, KIAA0645 
This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
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75 antibodies from 20 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
15 antibodies
NovoPro Bioscience Inc.
1 antibody
Biorbyt
3 antibodies
Invitrogen Antibodies
7 antibodies
Atlas Antibodies
2 antibodies
LifeSpan BioSciences, Inc.
13 antibodies
Abgent
1 antibody
Antibodies Incorporated / NeuroMab
2 antibodies
Affinity Biosciences
4 antibodies
Proteintech Group
1 antibody
Aviva Systems Biology
1 antibody
Novus Biologicals
2 antibodies
OriGene
1 antibody
ProSci
1 antibody
MyBioSource
2 antibodies
GeneTex
1 antibody
United States Biological
13 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
Creative Diagnostics
1 antibody
Abbexa
1 antibody