Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [2]
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Validation data
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- Product number
- MAB1799 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal STAT3 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human, mouse, and rat STAT3 in Western blots.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC, as supplied. 1 month, 2 to 8 degreesC under sterile conditions after opening. 6 months, -20 to -70 degreesC under sterile conditions after opening.
Submitted references Opa interacting protein 5 promotes metastasis of nasopharyngeal carcinoma cells by promoting EMT via modulation of JAK2/STAT3 signal.
Tumor-derived mesenchymal-stem-cell-secreted IL-6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer.
Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy.
Proangiogenic tumor proteins as potential predictive or prognostic biomarkers for bevacizumab therapy in metastatic colorectal cancer.
IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation.
Zheng YQ, Cui YR, Yang S, Wang YP, Qiu YJ, Hu WL
European review for medical and pharmacological sciences 2019 Jan;23(2):613-621
European review for medical and pharmacological sciences 2019 Jan;23(2):613-621
Tumor-derived mesenchymal-stem-cell-secreted IL-6 enhances resistance to cisplatin via the STAT3 pathway in breast cancer.
Xu H, Zhou Y, Li W, Zhang B, Zhang H, Zhao S, Zheng P, Wu H, Yang J
Oncology letters 2018 Jun;15(6):9142-9150
Oncology letters 2018 Jun;15(6):9142-9150
Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy.
Yamada K, Huang ZQ, Raska M, Reily C, Anderson JC, Suzuki H, Ueda H, Moldoveanu Z, Kiryluk K, Suzuki Y, Wyatt RJ, Tomino Y, Gharavi AG, Weinmann A, Julian BA, Willey CD, Novak J
Kidney international reports 2017 Nov;2(6):1194-1207
Kidney international reports 2017 Nov;2(6):1194-1207
Proangiogenic tumor proteins as potential predictive or prognostic biomarkers for bevacizumab therapy in metastatic colorectal cancer.
Bruhn MA, Townsend AR, Khoon Lee C, Shivasami A, Price TJ, Wrin J, Arentz G, Tebbutt NC, Hocking C, Cunningham D, Hardingham JE, BHI in collaboration with AGITG.
International journal of cancer 2014 Aug 1;135(3):731-41
International journal of cancer 2014 Aug 1;135(3):731-41
IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation.
Kolliputi N, Waxman AB
American journal of respiratory cell and molecular biology 2009 Mar;40(3):314-24
American journal of respiratory cell and molecular biology 2009 Mar;40(3):314-24
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human STAT3 by Western Blot. Detection of Human STAT3 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of STAT3 in Jurkat Human Cell Line by Flow Cytometry. Detection of STAT3 in Jurkat Human Cell Line by Flow Cytometry.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of STAT3 in HeLa Human Cell Line by Flow Cytometry. Detection of STAT3 in HeLa Human Cell Line by Flow Cytometry.