Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations [0]
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- Product number
- ABIN361959 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN361959, RRID:AB_10954162
- Product name
- anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (pTyr705) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr705 (A-P-Y (p) -L-K) derived from Human STAT3. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr705
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references PF-04691502 triggers cell cycle arrest, apoptosis and inhibits the angiogenesis in hepatocellular carcinoma cells.
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions.
Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.
Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
HER2-dependent MMP-7 expression is mediated by activated STAT3.
Serum-free mouse embryo cells generate a self-sustaining feedback loop for an astrocyte marker protein and respond to cytokines and bisphenol A in accordance with the subtle difference in their differentiation state.
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.
Wang FZ, Peng-Jiao, Yang NN, Chuang-Yuan, Zhao YL, Liu QQ, Fei HR, Zhang JG
Toxicology letters 2013 Jul 4;220(2):150-6
Toxicology letters 2013 Jul 4;220(2):150-6
Atrial natriuretic peptide suppresses Th17 development through regulation of cGMP-dependent protein kinase and PI3K-Akt signaling pathways.
Ma L, Li J, Wang G, Gong S, Zhang L, Li K, Ji X, Liu Y, Chen P, Xiang X
Regulatory peptides 2013 Feb 10;181:9-16
Regulatory peptides 2013 Feb 10;181:9-16
Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10.
García-Prieto E, González-López A, Cabrera S, Astudillo A, Gutiérrez-Fernández A, Fanjul-Fernandez M, Batalla-Solís E, Puente XS, Fueyo A, López-Otín C, Albaiceta GM
PloS one 2010 Oct 7;5(10):e13242
PloS one 2010 Oct 7;5(10):e13242
Significance and relationship between Cripto-1 and p-STAT3 expression in gastric cancer and precancerous lesions.
Zhang JG, Zhao J, Xin Y
World journal of gastroenterology 2010 Feb 7;16(5):571-7
World journal of gastroenterology 2010 Feb 7;16(5):571-7
Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.
Takeichi T, Sugiura K, Muro Y, Matsumoto K, Ogawa Y, Futamura K, Kaminuma O, Hashimoto N, Shimoyama Y, Saito H, Tomita Y
The Journal of investigative dermatology 2010 Dec;130(12):2760-7
The Journal of investigative dermatology 2010 Dec;130(12):2760-7
Endocrine glands-derived vascular endothelial growth factor protects pancreatic cancer cells from apoptosis via upregulation of the myeloid cell leukemia-1 protein.
Ren LN, Li QF, Xiao FJ, Yan J, Yang YF, Wang LS, Guo XZ, Wang H
Biochemical and biophysical research communications 2009 Aug 14;386(1):35-9
Biochemical and biophysical research communications 2009 Aug 14;386(1):35-9
HER2-dependent MMP-7 expression is mediated by activated STAT3.
Yuan G, Qian L, Shi M, Lu F, Li D, Hu M, Yu M, Shen B, Guo N
Cellular signalling 2008 Jul;20(7):1284-91
Cellular signalling 2008 Jul;20(7):1284-91
Serum-free mouse embryo cells generate a self-sustaining feedback loop for an astrocyte marker protein and respond to cytokines and bisphenol A in accordance with the subtle difference in their differentiation state.
Yamaguchi H, Zhu J, Yu T, Sasaki K, Umetsu H, Kidachi Y, Ryoyama K
Cell biology international 2007 Jun;31(6):638-44
Cell biology international 2007 Jun;31(6):638-44
Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation.
Yamaguchi H, Zhu J, Yu T, Sasaki K, Umetsu H, Kidachi Y, Ryoyama K
Toxicology 2006 Sep 21;226(2-3):131-42
Toxicology 2006 Sep 21;226(2-3):131-42
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