Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362567 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 725-729) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 725-729 (P-M-S-P-R) derived from Human STAT3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 725-729
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references A guanidine-rich regulatory oligodeoxynucleotide improves type-2 diabetes in obese mice by blocking T-cell differentiation.
Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling.
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells.
The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus.
Stat3 as an oncogene.
Activation of STAT transcription factors in oncogenic tyrosine kinase signaling.
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality.
Cheng X, Wang J, Xia N, Yan XX, Tang TT, Chen H, Zhang HJ, Liu J, Kong W, Sjöberg S, Folco E, Libby P, Liao YH, Shi GP
EMBO molecular medicine 2012 Oct;4(10):1112-25
EMBO molecular medicine 2012 Oct;4(10):1112-25
Canonical notch pathway protects hepatocytes from ischemia/reperfusion injury in mice by repressing reactive oxygen species production through JAK2/STAT3 signaling.
Yu HC, Qin HY, He F, Wang L, Fu W, Liu D, Guo FC, Liang L, Dou KF, Han H
Hepatology (Baltimore, Md.) 2011 Sep 2;54(3):979-88
Hepatology (Baltimore, Md.) 2011 Sep 2;54(3):979-88
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells.
Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, Ciliberto G, Moscinski L, Fernández-Luna JL, Nuñez G, Dalton WS, Jove R
Immunity 1999 Jan;10(1):105-15
Immunity 1999 Jan;10(1):105-15
The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus.
Heim MH
Journal of receptor and signal transduction research 1999 Jan-Jul;19(1-4):75-120
Journal of receptor and signal transduction research 1999 Jan-Jul;19(1-4):75-120
Stat3 as an oncogene.
Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C, Darnell JE Jr
Cell 1999 Aug 6;98(3):295-303
Cell 1999 Aug 6;98(3):295-303
Activation of STAT transcription factors in oncogenic tyrosine kinase signaling.
Garcia R, Jove R
Journal of biomedical science 1998;5(2):79-85
Journal of biomedical science 1998;5(2):79-85
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality.
Takeda K, Noguchi K, Shi W, Tanaka T, Matsumoto M, Yoshida N, Kishimoto T, Akira S
Proceedings of the National Academy of Sciences of the United States of America 1997 Apr 15;94(8):3801-4
Proceedings of the National Academy of Sciences of the United States of America 1997 Apr 15;94(8):3801-4
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