ABIN362568

antibody from antibodies-online

Targeting: STAT3 APRF

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN362568

Provider

antibodies-online

Product name

anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) (AA 725-729) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 725-729 (P-M-S-P-R) derived from Human STAT3. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 725-729

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells.

Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, Ciliberto G, Moscinski L, Fernández-Luna JL, Nuñez G, Dalton WS, Jove R
Immunity 1999 Jan;10(1):105-15

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The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus.

Heim MH
Journal of receptor and signal transduction research 1999 Jan-Jul;19(1-4):75-120

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Stat3 as an oncogene.

Bromberg JF, Wrzeszczynska MH, Devgan G, Zhao Y, Pestell RG, Albanese C, Darnell JE Jr
Cell 1999 Aug 6;98(3):295-303

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Activation of STAT transcription factors in oncogenic tyrosine kinase signaling.

Garcia R, Jove R
Journal of biomedical science 1998;5(2):79-85

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Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality.

Takeda K, Noguchi K, Shi W, Tanaka T, Matsumoto M, Yoshida N, Kishimoto T, Akira S
Proceedings of the National Academy of Sciences of the United States of America 1997 Apr 15;94(8):3801-4